The Rabbit Anti-ERR alpha Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to ESRRA, and Estrogen Related Receptor alpha. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-ERR alpha Antibody has been shown to work in the following applications: Flow Cytometry, Immunoprecipitation, and Western Blot.
Description
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle