The BACE2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BACE2. This antibody recognizes Human, and Rat antigen. The BACE2 Antibody has been shown to work in the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672