MyBioSource.com's Rabbit Anti-Mast Cell Tryptase Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-Mast Cell Tryptase Antibody was generated using TPSAB1 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed: 18854315)