The CD2AP Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD2AP. This antibody recognizes Human, and Rat antigen. The CD2AP Antibody has been shown to work in the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis