MyBioSource.com's Anti-SHP2 Rabbit Monoclonal Antibody is a Rabbit monoclonal antibody. The Anti-SHP2 Rabbit Monoclonal Antibody was generated using PTPN11 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity