MyBioSource.com's Rabbit Anti-Claudin 2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot. The Rabbit Anti-Claudin 2 Antibody was generated using Claudin 2, and CLDN2 as the antigen and it reacts with Human, and Mouse.
Description
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. The tight junctions are specialized regions of cell to cell contact. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands. Different tissues exhibit different Claudin composition