The Anti-EIF2C3 Rabbit Monoclonal Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to AGO3. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-EIF2C3 Rabbit Monoclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4