MyBioSource.com's Anti-APAF1 Rabbit Monoclonal Antibody is a Rabbit monoclonal antibody. The Anti-APAF1 Rabbit Monoclonal Antibody was generated using APAF1 as the antigen. It reacts with Human, and Mouse. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis