The DOK5 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Docking Protein 5, and DOK5. This antibody recognizes Mouse, and Rat antigen. The DOK5 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants