The MBD2 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to MBD2. This antibody recognizes Human antigen. The MBD2 Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters