The Rabbit Anti-Beta 2 Microglobulin Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to B2M, and Beta-2-microglobulin. This antibody recognizes Human antigen. The Rabbit Anti-Beta 2 Microglobulin Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Description: Beta-2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the beta-2-microglobulin protein is encoded by the B2M gene. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Protein Function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system