The Anti-JAM1 Rabbit Monoclonal Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to F11R. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-JAM1 Rabbit Monoclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus