The Anti-Atg4B Rabbit Monoclonal Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to ATG4B. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-Atg4B Rabbit Monoclonal Antibody has been shown to work in the following applications: Flow Cytometry, and Western Blot.
Description
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms