MyBioSource.com's Rabbit Anti-Caspase-10 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-Caspase-10 Antibody was generated using CASP10, and Caspase 10 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-:-AMC and Asp-Glu-Val-Asp-:-AMC