The Rabbit Anti-BACE1/Bace Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to BACE1, and Beta-Secretase 1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-BACE1/Bace Antibody has been shown to work in the following applications: Immunoprecipitation, and Western Blot.
Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase