MyBioSource.com's Rabbit Anti-Atg16L1/Atg16 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-Atg16L1/Atg16 Antibody was generated using ATG16L1 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane