MyBioSource.com's Rabbit Anti-pro Caspase 9 Antibody is a Rabbit monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP)