MyBioSource.com's Rabbit Anti-Cyclin G1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot. The Rabbit Anti-Cyclin G1 Antibody was generated using Cyclin G1 as the antigen and it reacts with Human.
Description
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression. It is p53-responsive gene that the transcriptional activation of Cyclin G1 can be induced by tumor protein p53