The Anti-IRF2 Rabbit Monoclonal Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to IRF2. This antibody recognizes Human, and Mouse antigen. The Anti-IRF2 Rabbit Monoclonal Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation