The PRAME Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PRAME. This antibody recognizes Human, Mouse, and Rat antigen. The PRAME Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants