The Rabbit Anti-Interferon Receptor alpha Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to IFNAR1. This antibody recognizes Human antigen. The Rabbit Anti-Interferon Receptor alpha Antibody has been shown to work in the following applications: Western Blot.
Description
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed: 2153461, PubMed: 7665574, PubMed: 10049744, PubMed: 14532120, PubMed: 15337770, PubMed: 21854986). Functions in general as heterodimer with IFNAR2 (PubMed: 7665574, PubMed: 10049744, PubMed: 21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (PubMed: 7665574, PubMed: 21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity)