The Rabbit Anti-IRE1 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to ERN1. This antibody recognizes Human antigen. The Rabbit Anti-IRE1 Antibody has been shown to work in the following applications: Western Blot.
Description
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis