The Anti-eIF4E Mouse mAb Antibody from MyBioSource.com is a Mouse Monoclonal antibody to EIF4E. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-eIF4E Mouse mAb Antibody has been shown to work in the following applications: Western Blot.
Description
Entrez Summary: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants