The GSK3alpha (Phospho-Ser21) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GSK3A. This antibody recognizes Human antigen. The GSK3alpha (Phospho-Ser21) Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
GSK3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK3 alpha and GSK3 beta, which are structurally similar, but functionally non-identical. GSK3alpha is inhibited by phosphorylation at S21 by Akt and other kinases. Dysregulated GSK3 has been implicated in several diseases including type II diabetes, Alzheimers disease, and cancer