TGF-beta RII Antibody MAB532 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTGF-beta RII Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $579.00Supplier Page View Company Product Page
Catalog NumberMAB532
NCBI Gene AliasesTAAD2, AAT3, TBRII, RIIC, TBR-II, LDS2B, MFS2, 1110020H15Rik, TbetaR-II, TGFR-2, TBR-ii, LDS2, RIIDN, TGFbeta-RII, TbetaRII, DNIIR, tbetaR-II, FAA3, LDS1B
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot
TargetTGF-beta RII
HostRat
Clone129502
Quantity500 ug (also 25 ug)
Conjugate/TagUnconjugated
ReactivityMouse
IsotypeIgG2b
NCBI Full Gene Nametransforming growth factor beta receptor 2, transforming growth factor, beta receptor II
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF¿ß RII, Ile24-Asp184, Accession # Q62312
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse TGF¿ß RII in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with with recombinant rat MIS RII, recombinant mouse TGF¿ß RI, recombinant human (rh) TGF¿ß RII, rhTGF¿ß RIIb, or rhTGF¿ß RIII.

Sizes Available: 500 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppressionNature communicationsJuly 12, 2024Zahraeifard S, Xiao Z, So JY, Ahad A, Montoya S, Park WY, Sornapudi T, Andohkow T, Read A, Kedei N, et al.24E10), NF1 (1:200, abcam, ab17963), TSC1 (1:200, ThermoFisher, PA5-20131), TGFβRII (1:100, R&D System, MAB532, C129502), followed by incubation with secondary antibodies goat anti-mouse Alexa Fluor 594 (1:500,

(2) Bone marrow-derived extracellular vesicles carry the TGF-β signal transducer Smad2 to preserve hematopoietic stem cells in miceCell death discoveryApril 5, 2023Gautheron F, Georgievski A, Garrido C, Quéré R.BD Biosciences) used as a loading control. We also used anti-TGF-β-RI (ABF17-I, Merck) and anti-TGF-β-RII (MAB532, R&D Systems) antibodies. Appropriate secondary anti-rat, anti-mouse or anti-rabbit antibodies conjugated

(3) Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarctionBiochimica et biophysica acta. Molecular basis of diseaseJune 1, 2019Wang Y, Liu CL, Fang W, Zhang X, Yang C, Li J, Liu J, Sukhova GK, Gurish MF, Libby P, et al.eBioscience, San Diego, CA), α-SMA (1:750, Cat# 14968s, Cell Signaling Technology), TGF-β1 (1:100, Cat# MAB532, R&D Systems, Minneapolis, MN), p-Smad2 (1:100, Cat# AB3849, EMD Millipore, Billerica, MA), and p-Smad3

(4) Transforming growth factor-beta1 sensitivity is altered in Abl-Myc- and Raf-Myc-induced mouse pre-B-cell tumorsStem CellsDecember 1, 2006Letterio J, Rudikoff E, Voong N, Bauer SR.

(5) Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesisEuropean heart journalJanuary 1, 0001"Meng Z, Zhang S, Li W, Wang Y, Wang M, Liu X, Liu CL, Liao S, Liu T, Yang C, et al."(1:1000, 692802, BioLegend), rat anti-TGFBR-1 (1:1000, MAB5871, R&D Systems), and rat anti-TGFBR2 (1:1000, MAB532, R&D Systems), and GAPDH (1:2000, 2118S, Cell Signaling Technology) antibodies. Western blot signals

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Mouse TGF-beta RII Antibody

TGF-beta RII Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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TGF-beta RII Antibody from R&D Systems, a Bio-Techne Brand

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