Human PDGF R alpha Antibody MAB1264 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman PDGF R alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $449.00Supplier Page View Company Product Page
Catalog NumberMAB1264
Quantity250 ug (also 25 ug)
ApplicationsFlow Cytometry,Immunoprecipitation,Immunocytochemistry
ReactivityHuman,Mouse
Conjugate/TagUnconjugated
FormatSupplied as a 0.2 µm filtered solution in PBS. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
PurityProtein A or G purified from ascites
HostMouse
IsotypeIgG1
ClonePRa292
TargetPDGF R alpha
Antibody TypePrimary Antibodies
ClonalityMonoclonal
ImmunogenHuman osteosarcoma cell membrane extracts
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C, as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 6 months, -20 to -70 °C under sterile conditions after opening
NCBI Full Gene Nameplatelet derived growth factor receptor alpha
NCBI Gene AliasesCD140A, PDGFR-2, PDGFR2

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) PDGFRA K385 mutants in myxoid glioneuronal tumors promote receptor dimerization and oncogenic signalingScientific reportsMarch 26, 2024de Villenfagne L, Sablon A, Demoulin JB.Flow cytometry Ba/F3 cells were harvested, washed in PBS and stained with a primary mouse anti-PDGFRα antibody (#MAB1264, R&D systems, Minneapolis, MN, USA, MAB1264) for 30 min at 4 °C. Cells were then washed and incubated

(2) Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancreatic cancerOncology reportsDecember 1, 2020Khan T, Seddon AM, Dalgleish AG, Khelwatty S, Ioannou N, Mudan S, Modjtahedi H.whereas mouse anti-HER3 (MAB3481), anti-HER4 (MAB11311), ALK7 (MAB77491), HGF R/c-MET (MAB3582), PDGFRα (MAB1264), PDGFRβ (MAB1263) and IGF-IR (MAB391) were purchased from R&D Systems (Europe Ltd. UK) and Insight

(3) A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastomaScientific reportsMarch 20, 2019Stringer BW, Day BW, D'Souza RCJ, Jamieson PR, Ensbey KS, Bruce ZC, Lim YC, Goasdoué K, Offenhäuser C, Akgül S, et al.1:100), EGFR (in-house, M528, 0.5 μg/ml), EGFRvIII (in-house, 806, 0.5 μg/ml), PDGFRα (R&D Systems, MAB1264, 0.5 μg/ml), EphA2 (in-house, 1F7, 0.5 μg/ml), EphA3 (in-house, IIIA4, 0.5 μg/ml), EphA4 (in-house,

(4) PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutationsOncogeneMay 15, 2014Velghe AI, Van Cauwenberghe S, Polyansky AA, Chand D, Montano-Almendras CP, Charni S, Hallberg B, Essaghir A, Demoulin JB.cytometry after staining with a monoclonal anti-PDGFRA antibody (R&D systems, Minneapolis, MN, USA, MAB1264) and anti-mouse immunoglobulin labeled with phycoerythrin (Jackson Laboratories, Bar Harbor, ME, USA).

(5) Alveolar macrophages are critical for the inhibition of allergic asthma by mesenchymal stromal cellsJournal of immunology (Baltimore, Md. : 1950)December 15, 2013Mathias LJ, Khong SM, Spyroglou L, Payne NL, Siatskas C, Thorburn AN, Boyd RL, Heng TS.

(6) Human glial-restricted progenitors survive, proliferate, and preserve electrophysiological function in rats with focal inflammatory spinal cord demyelinationGliaMarch 1, 2011Walczak P, All AH, Rumpal N, Gorelik M, Kim H, Maybhate A, Agrawal G, Campanelli JT, Gilad AA, Kerr DA, et al.protein (MBP) (1:500, MCA409S; AbD Serotec; Kidlington, Oxford). A2B5 (MAB1416, R&D Systems), PDGFRalpha (MAB1264, R&D Systems), Nestin (MAB5326, Millipore), PSA-NCAM (MAB5324, Millipore), CD68 (#M0718, DakoCytomation),

(7) Mesenchymal stem cell abnormalities in patients with multiple myelomaLeukemia & lymphomaOctober 1, 2007Garderet L, Mazurier C, Chapel A, Ernou I, Boutin L, Holy X, Gorin NC, Lopez M, Doucet C, Lataillade JJ.

(8) Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptorJournal of immunology (Baltimore, Md. : 1950)October 1, 2007Zhang M, Veselits M, O'Neill S, Hou P, Reddi AL, Berlin I, Ikeda M, Nash PD, Longnecker R, Band H, et al.

(9) The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activitiesStem CellsJuly 1, 2007Ponte AL, Marais E, Gallay N, Langonné A, Delorme B, Hérault O, Charbord P, Domenech J.

(10) Vascular endothelial growth factor can signal through platelet-derived growth factor receptorsThe Journal of cell biologyMay 7, 2007Ball SG, Shuttleworth CA, Kielty CM.(wt/vol) protein A–Sepharose (GE Healthcare), and then incubated with monoclonal anti–human PDGFRα (MAB1264) or PDGFRβ (MAB1263; R&D Systems) overnight at 4°C. Immune complexes were isolated by incubation with

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Human PDGF R alpha Antibody

PDGF R alpha Antibody

PDGF R alpha Antibody

Human PDGF R alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (10)

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Human PDGF R alpha Antibody from R&D Systems, a Bio-Techne Brand

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