Mouse IgG2A Isotype Control MAB003 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse IgG2A Isotype Control
CompanyR&D Systems, a Bio-Techne Brand
Price $249.00Supplier Page View Company Product Page
Catalog NumberMAB003
Quantity500 ug
ApplicationsControl
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
TargetIgG2A
ReactivityMouse
IsotypeIgG2a
Clone20102
HostMouse
Antibody TypeIsotype Controls
ImmunogenKLH
ClonalityMonoclonal
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Many but not all pathogen-associated molecular patterns aggravate neurogenic heterotopic ossification after spinal cord injuryJ Biomed SciApril 10, 2026Selwin G. Samuel, Hsu-Wen Tseng, Bastien Rival, Valérie Barbier, Kavita Bisht, Marjorie Salga, Shrutika M Mate, Whitney Fleming, François Genêt, Sébastien Banzet, et al.anti-human OSM monoclonal antibody (MAB295, Clone 17,001, Bio-Techne) or mouse IgG2a isotype control (Cat# MAB003, Clone 20,102, Bio-Techne) were used at 10 µg/ml with a 2-h pre-incubation in CM prior to addition to

(2) Human amnion epithelial cells induce M2 macrophage polarisation partially via M-CSF secretion but independently of extracellular vesicles in vitroFrontiers in ImmunologyJanuary 29, 2026Louise Zeijlon, Snehil Budhwar, Robert Lindau, Stefan Bencina, Helen Kaipe, Maria C. Jenmalm, Roberto Gramignoli, Johanna RaffetsederUSA). The M-CSF antibody or its corresponding isotype control antibody (clone #20102, catalogue number: MAB003, R&D Systems) was added to RPMI medium containing AEC-CM, 5 ng/ml GM-CSF, 10% FCS and 1% penicillin-streptomycin/L-glutamine,

(3) Potent antioxidant and mitochondrial-protective effects of ATH434, a moderate affinity iron chaperoneThe Journal of biological chemistrySeptember 1, 2025Bailey DK, Nihlawi R, Bradbury MJ, Bond S, Kosman DJ.#NBP1-77686, Novus), mouse anti- β-III-tubulin (Cat #MAB1195, Biotechne), mouse IgG2A isotype control (Cat #MAB003, Biotechne). Coverslips were then incubated with secondary antibody at 1:1000 in 1% BSA with donkey

(4) Genetic ancestry shapes dengue virus infection in human skin explantsProceedings of the National Academy of Sciences of the United States of AmericaJuly 15, 2025Castanha PMS, Martí MM, Duangkhae P, Taddonio JM, Cooper KL, Wallace M, Kettenburg G, Erdos G, Chavva H, Alex A, et al.neutralizing antibody to human IL-1β (R&D Systems, MAB601-25), 30 ng isotype control antibody (R&D Systems, MAB003 and MAB002), or a combination of these. For these experiments, arrays were applied prior to virus inoculation. Immunohistochemistry

(5) Long-term culture of chicken tracheal organoids for the purpose of avian influenza virus researchVirol JApril 15, 2025Anja C. M. de Bruin, Mart M. Lamers, Bart L. Haagmans, Lonneke M. Leijten, Ron A. M. Fouchier, Mathilde Richard1 h at RT with 5 µg/mL anti-NP antibody (H16-L10-4R5 (ATCC HB-65)) or mouse IgG2α isotype control (MAB003; R&D Systems) diluted in PBS with 0.1% BSA, washed thrice with PBS 0.05% TWEEN, stained for 1 h at RT

(6) Loss of CYLD promotes splenic marginal zone lymphomaHemasphereMarch 17, 2025Athanasios Pseftogas, Jessica Bordini, Silvia Heltai, Ferdinando Bonfiglio, Georgios Gavriilidis, Vasileios Vasileiou, Sofoklis Keisaris, Daniela Belloni, Caterina Taccetti, Pamela Ranghetti, et al.(#HY‐12276). Mouse anti‐hCCR7 mAb (#MAB197, 150503 clone, IgG2a) and the respective isotype control (#MAB003, IgG2a) were purchased from R&D Systems. Patient samples Primary peripheral blood and bone marrow

(7) Genetic and pharmacological targeting of mTORC1 in mouse models of arteriovenous malformation expose non-cell autonomous signalling in HHTAngiogenesisMarch 1, 2025Antonio Queiro-Palou, Yi Jin, Lars JakobssonR&D Systems, respectively) or isotype control antibodies (15 mg/kg, IgG2b, MAB004; 15 mg/kg, IgG2a, MAB003; R&D Systems, respectively) at P3, P4 and P5 and tissues were harvested at P6. Whole-mount staining

(8) Sodium valproate enhances efficacy of NKG2D CAR-T cells against glioblastomaFront ImmunolJanuary 14, 2025Junchen Liu, Kun Dai, Muhammad Auwal Saliu, Mansur Dabai Salisu, Jiangyu Gan, Lukman Olalekan Afolabi, Dehong Yan, Guizhong Zhang, Maoxuan Liu, Xiaochun Wanantibody (Cat# MAB1298), anti-human ULBP3 antibody (Cat# MAB1517), and mouse IgG2a isotype control (Cat# MAB003) were obtained from R&D Systems (USA). Anti-human ULBP4 antibody (Cat# sc-53133) was obtained from Santa Cruz Biotechnology

(9) A Recombinant Antibody Against ALK2 Promotes Tissue Iron Redistribution and Contributes to Anemia Resolution in a Mouse Model of Anemia of InflammationAmerican Journal of HematologyJanuary 10, 2025Chia‐Yu Wang, Emiliano Melgar‐Bermudez, Diana Welch, Kevin B. Dagbay, Seemana Bhattacharya, Evan Lema, Tyler Daman, Olivia Sierra, Radina Todorova, Papa Makhtar Drame, et al.analytical size exclusion chromatography (Superdex 200 Increase 5/150 GL, Cytiva) and SDS‐PAGE. IgG2A (MAB003; R&D Systems) was used as an isotype control in all experiments. 2.3 Surface Plasmon Resonance The

(10) Enhanced and sustained biodistribution of HIV-1 neutralizing antibody VRC01LS in human genital and rectal mucosaNature CommunicationsNovember 28, 2024Maria P. Lemos, Rena D. Astronomo, Yunda Huang, Sandeep Narpala, Madhu Prabhakaran, Philipp Mann, Carmen A. Paez, Yiwen Lu, Gregory J. Mize, Hayley Glantz, et al.incubated with either 10.7 µg/ml 5C9 (J. Mascola lab) or mouse IgG2a isotype control (R&D Systems cat# MAB003, clone 20102; Lot# MV0917051, MV0918031, MV0919011 and MV092001) diluted in primary antibody diluent

(11) A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodelingNature Cardiovascular ResearchJuly 8, 2024Hanqiang Deng, Jiasheng Zhang, Yewei Wang, Divyesh Joshi, Xinchun Pi, Sarah De Val, Martin A. SchwartzAntibodies for BMP9 (MAB3209, clone #360107), BMP10 (MAB2926, clone #462732), IgG2A isotype control (MAB003, clone #20102) and IgG2B isotype control (MAB004, clone #20116) were purchased from R&D Systems. Secondary

(12) Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injuryJCI insightMarch 8, 2024Wang X, Du W, Li Y, Yang HH, Zhang Y, Akbar R, Morgan H, Peng T, Chen J, Sadayappan S, et al.Then we added rSec (200 ng/mL, R&D Systems, catalog 7837-ST) or control IgG2a (R&D Systems, catalog MAB003) for 12 hours, followed by efferocytosis and RT-qPCR assays. For the Sectm1a/Gitr signaling cascade

(13) Species-specific emergence of H7 highly pathogenic avian influenza virus is driven by intrahost selection differences between chickens and ducksPLOS PathogensFebruary 26, 2024Anja C. M. de Bruin, Monique I. Spronken, Adinda Kok, Miruna E. Rosu, Dennis de Meulder, Stefan van Nieuwkoop, Pascal Lexmond, Mathis Funk, Lonneke M. Leijten, Theo M. Bestebroer, et al.sections were incubated with 5 μg/mL anti-NP antibody (ATCC HB-65), or mouse IgG2α isotype control (MAB003; R&D Systems) for 1 h at room temperature in PBS/0.1% BSA, followed by 1 h incubation with 10 μg/mL

(14) Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infectionFrontiers in ImmunologyJanuary 22, 2024Margit Anthofer, Markus Windisch, Rosa Haller, Sandra Ehmann, Sebastian Wrighton, Michael Miller, Lorenz Schernthanner, Iris Kufferath, Silvia Schauer, Barbara Jelušić, et al.(R&D Systems Cat# MAB13001, RRID: AB_2143621) or the mouse IgG2A isotype control (R&D Systems Cat# MAB003, RRID: AB_357345). After 24 h, NKL cells were stained either with the FITC anti-human CD94 antibody

(15) Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsiesScienceJanuary 19, 2024Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, et al.produced in house; 35I9 was purchased from Abcam (cat. ab27156); mouse IgG2a control (clone 20102, cat. MAB003), anti-FcγRII/III (rat anti-mouse, clone 190909, cat. MAB1460), and anti-FcγRI (rat anti-mouse, clone

(16) Lactobacillus from the Altered Schaedler Flora maintain IFNγ homeostasis to promote behavioral stress resilienceBrain, behavior, and immunityJanuary 1, 2024Merchak AR, Wachamo S, Brown LC, Thakur A, Moreau B, Brown RM, Rivet-Noor CR, Raghavan T, Gaultier A.housed in SPF conditions. Anti-IFNγ (R&D Systems; MAB485-SP) and IgG2A isotype control (R&S Systems; MAB003) were administered i.p. at a dose of 150 μg/mouse 14 h before stress. IFNγ (R&D Systems; 485-MI-100)

(17) Protocol to characterize extracellular c-Src tyrosine kinase function through substrate interaction and phosphorylationSTAR protocolsDecember 15, 2023Omini MP, Alsalih D, Votra SD, Bourboulia D.#ab172730; RRID: AB_2687931 "Mouse IgG2A isotype control, clone # 20102Dilution: 1 μg/mL",R&D Systems,Cat #MAB003; RRID: AB_357345 "Rabbit anti-Src mAb (32G6)Dilution: 1:5,000 (WB); 1 μg/mL for treatment",Cell Signaling Technology

(18) Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney diseaseNature communicationsNovember 15, 2023Gnirck AC, Philipp MS, Waterhölter A, Wunderlich M, Shaikh N, Adamiak V, Henneken L, Kautz T, Xiong T, Klaus D, et al.

(19) A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor CellsMolecular Cancer TherapeuticsOctober 2, 2023Geetha Venkateswaran, Paul C. McDonald, Shawn C. Chafe, Wells S. Brown, Zachary J. Gerbec, Shannon J. Awrey, Seth J. Parker, Shoukat DedharWestern blotting Mouse anti-human CAIX (R and D Systems, MAB2188, RRID:AB_2066530); mouse IgG2A (R and D Systems, MAB003, RRID:AB_357345); goat anti-human CAIX (R and D Systems, AF2188, RRID:AB_416562) – 1:1,000; rabbit anti-human

(20) The pro-inflammatory response to influenza A virus infection is fueled by endothelial cellsLife science allianceJuly 1, 2023Bauer L, Rijsbergen LC, Leijten L, Benavides FF, Noack D, Lamers MM, Haagmans BL, de Vries RD, de Swart RL, van Riel D.with mouse IgG2a-anti–IAV NP (Clone Hb65; EVL Laboratories), 5 μg/ml or mouse IgG2a isotype control (MAB003; R&D Systems), 2.5 μg/ml in PBS/0.1% BSA for 1 h at RT. After washing, sections were incubated with

Be the First to Write a Review!

Mouse IgG2A Isotype Control

Mouse IgG2A Isotype Control

Mouse IgG2A Isotype Control

Mouse IgG2A Isotype Control from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (117)

Reviews

Mouse IgG2A Isotype Control from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map