SENP1 (C-12) Antibody sc-271360 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSENP1 (C-12) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-271360
NCBI Gene AliasesD15Ertd528e, suPr-2, 2310046A20Rik, E330036L07Rik, SuPr-2
ApplicationsWB, IP, IF, ELISA
Hostmouse
CloneC-12
Quantity200 µg/ml
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
Reactivitymouse, rat, human
ClonalityMonoclonal
FormatPurified
NCBI Full Gene NameSUMO specific peptidase 1, SUMO1/sentrin specific peptidase 1
TargetSENP1
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) FSTL1 promotes alveolar epithelial cell aging and worsens pulmonary fibrosis by affecting SENP1-mediated DeSUMOylationCell biology internationalOctober 1, 2023Sun W, Yang X, Chen L, Guo L, Huang H, Liu X, Yang Y, Xu Z.

(2) Aberrant SENP1-SUMO-Sirt3 Signaling Causes the Disturbances of Mitochondrial Deacetylation and Oxidative Phosphorylation in Prion-Infected Animal and Cell ModelsACS chemical neuroscienceMay 3, 2023Chen DD, Shi Q, Liu X, Liang DL, Wu YZ, Fan Q, Xiao K, Chen C, Dong XP.

(3) A stress-induced cilium-to-PML-NB route drives senescence initiationNature communicationsApril 3, 2023Ma X, Zhang Y, Zhang Y, Zhang X, Huang Y, He K, Chen C, Hao J, Zhao D, LeBrasseur NK, et al.1:200 for western blotting), HYLS1 (D-9) (sc-376721; dilution 1:200 for immunofluorescent), SENP1 (sc-271360; dilution 1:500 for immunofluorescent and western blotting), GST tag (B-14) (sc-138; dilution 1:1000

(4) SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammationNature communicationsNovember 22, 2022Yan L, Zhang T, Wang K, Chen Z, Yang Y, Shan B, Sun Q, Zhang M, Zhang Y, Zhong Y, et al.1:1000), FADD (Abcam, ab124812, 1:1000), FADD (Santa Cruz, SC-6036, 1:100 for IP), SENP1 (Santa Cruz, sc-271360, 1:1000), TRADD (Santa Cruz, sc-7868, 1:500), ERK1/2 (Proteintech, 67170-1-Ig, 1:1000), JNK (Proteintech,

(5) SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophyCell reportsNovember 22, 2022Amrute-Nayak M, Gand LV, Khan B, Holler T, Kefalakes E, Kosanke M, Kraft T, Nayak A.

(6) SENP1 Protects Against Pressure Overload-Induced Cardiac Remodeling and Dysfunction Via Inhibiting STAT3 SignalingJournal of the American Heart AssociationNovember 15, 2022Yang D, Fan D, Guo Z, Liu FY, Wang MY, An P, Yang Z, Tang QZ.

(7) Host SUMOylation Pathway Negatively Regulates Protective Immune Responses and Promotes Leishmania donovani SurvivalFrontiers in cellular and infection microbiologyJanuary 1, 2022Singhal J, Madan E, Chaurasiya A, Srivastava P, Singh N, Kaushik S, Kahlon AK, Maurya MK, Marothia M, Joshi P, et al.1:1,000), AOS-1 (Santa Cruz #sc-398080; 1:1,000), UBC9 (Santa Cruz #sc-271057; 1:1,000), SENP1 (Santa Cruz #sc-271360; 1:1,000), β-actin (Santa Cruz #sc-8432; 1:1,000), Beclin-1 (CST, Danvers, MA, USA; #3495T, 1:1,000),

(8) β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High-Fat Diet-Fed MiceDiabetesNovember 1, 2021Lin H, Smith N, Spigelman AF, Suzuki K, Ferdaoussi M, Alghamdi TA, Lewandowski SL, Jin Y, Bautista A, Wang YW, et al.U-Plex Mouse Glucagon ELISA Kit [Mesoscale Discovery]). Western Blotting SENP1 antibody-C12 (1:500, sc-271360; Santa Cruz Biotechnology), SUMO1 antibody (1:1,000, ab133352; Abcam), and β-actin antibody (1:2,000,

(9) SENP1 participates in Irinotecan resistance in human colon cancer cellsJournal of cellular biochemistryOctober 1, 2021Chen MC, Nhan DC, Hsu CH, Wang TF, Li CC, Ho TJ, Mahalakshmi B, Chen MC, Yang LY, Huang CY.

(10) SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1The Journal of biological chemistryJanuary 1, 2021Wang JQ, Lin ZC, Li LL, Zhang SF, Li WH, Liu W, Song BL, Luo J.(#F3165; Sigma), mouse monoclonal anti-His (#66005-1-Ig; ProteinTech), and mouse monoclonal anti-SENP1 (#sc-271360; Santa Cruz). The monoclonal antibody against c-Myc was prepared from hybridomas (ATCC, Clone 9E10).

(11) TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and SpecificityFrontiers in cell and developmental biologyJanuary 1, 2021Li YY, Cen H, Gong BN, Mai S, Wang QL, Mou S, Li Y.

(12) Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic CellsCell reportsSeptember 15, 2020Theurillat I, Hendriks IA, Cossec JC, Andrieux A, Nielsen ML, Dejean A.(Cell Signaling, 4392), Znf451 (Sigma, SAB2108741), Ranbp2 (Santa Cruz, SC74518), Senp1 (Santa Cruz, SC271360), Senp2 (Santa Cruz, SC67075), Senp3 (Cell Signaling, 5591), Senp5 (Abcam, ab47631), Senp6 (Thermo Fisher Scientific

(13) Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cellsOncogeneFebruary 1, 2019Traboulsi T, El Ezzy M, Dumeaux V, Audemard E, Mader S.Antibodies ERα 60 C (Millipore 04-820), β-actin (Sigma A5441), SENP1 C-12 (Santa Cruz Biotechnology sc-271360), horseradish peroxidase (HRP)-conjugated anti-rabbit (Cedarlane 111-035-003) and HRP-conjugated anti-mouse

(14) Modularly Constructed Synthetic Granzyme B Molecule Enables Interrogation of Intracellular Proteases for Targeted CytotoxicityACS synthetic biologyAugust 18, 2017Ho P, Ede C, Chen YY.

(15) Dynamic regulation of HIF1Α stability by SUMO2/3 and SENP3 in the human placentaPlacentaApril 1, 2016Bhattacharjee J, Alahari S, Sallais J, Tagliaferro A, Post M, Caniggia I.

(16) Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cellsThe Journal of clinical investigationOctober 1, 2015Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, et al.by Western blot using a mouse monoclonal SENP1 antibody (1:500) from Santa Cruz Biotechnology Inc. (sc-271360). Statistics. Data analysis was performed using FitMaster (HEKA Electronik) and GraphPad Prism (v6.0c).

(17) Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damageNature communicationsNovember 18, 2014Park JH, Lee SW, Yang SW, Yoo HM, Park JM, Seong MW, Ka SH, Oh KH, Jeon YJ, Chung CH.

(18) Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcriptionThe FEBS journalAugust 1, 2014Chhunchha B, Fatma N, Kubo E, Singh DP.USA), Sp1 monoclonal (sc-17824; Santa Cruz Biotechnologies, Santa Cruz, CA, USA) and Senp1 monoclonal (sc-271360; Santa Cruz Biotechnologies, Santa Cruz, CA, USA). Membranes were incubated with horseradish peroxidase-conjugated

(19) SUMOylation alterations are associated with multidrug resistance in hepatocellular carcinomaMolecular medicine reportsMarch 1, 2014Qin Y, Bao H, Pan Y, Yin M, Liu Y, Wu S, Li H.SUMO‑1 (catalog no. sc‑5308), Aos1 (catalog no. sc‑271592), Uba2 (catalog no. sc‑136359) and SENP1 (catalog no. sc‑271360) were purchased from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA, USA). Cell lines. The HepG2 human

(20) Global SUMOylation facilitates the multimodal neuroprotection afforded by quercetin against the deleterious effects of oxygen/glucose deprivation and the restoration of oxygen/glucoseJournal of neurochemistryJanuary 1, 0001"Lee YJ, Bernstock JD, Nagaraja N, Ko B, Hallenbeck JM."dose-dependent manner (Figure 2B) when we used an anti-SENP1 antibody from Santa Cruz Biotechnology (C12, cat# sc-271360), which had been raised against amino acids 361–425 (i.e. the middle part of the protein as SENP1 consists

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SENP1 (C-12) Antibody

SENP1 (C-12) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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SENP1 (C-12) Antibody from Santa Cruz Biotechnology, Inc.

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