Human HGFR/c-MET Biotinylated Antibody BAF358 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman HGFR/c-MET Biotinylated Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $579.00Supplier Page View Company Product Page
Catalog NumberBAF358
Quantity50 ug
ApplicationsElectrochemiluminescent Assay,ELISA Development (Capture),Flow Cytometry,Western Blot,ELISA Detection (Matched Antibody Pair),Immunocytochemistry
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Conjugate/TagBiotin
ConcentrationLYOPH
PurityAntigen Affinity-purified
IsotypeIgG
ReactivityHuman
HostGoat
TargetHGFR/c-MET
Antibody TypePrimary Antibodies
NCBI Gene Aliasesc-Met, HGFR, AUTS9, DA11, RCCP2, DFNB97
NCBI Full Gene NameMET proto-oncogene, receptor tyrosine kinase
ImmunogenMouse myeloma cell line NS0-derived recombinant human HGF R/c-MET, Glu25-Thr932, Accession # P08581
ClonalityPolyclonal
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Biotin

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Autocrine signaling by receptor tyrosine kinases in urothelial carcinoma of the bladderPloS oneJanuary 1, 2021Lee YH, Lee MM, De Silva DM, Roy A, Wright CE, Wong TK, Costello R, Olaku O, Grubb RL 3rd, Agarwal PK, et al.obtained from Cell Signaling Technology (Danvers, Massachusetts USA). Antibodies against Met (cat. # BAF358, AF276), RYK (cat. #AF4907), CSF1 (cat. #AF216), CSF1R (cat. #MAB3291) and GAS6 (cat. # AF885) were

(2) Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma CellsCell systemsNovember 18, 2020Gerosa L, Chidley C, Fröhlich F, Sanchez G, Lim SK, Muhlich J, Chen JY, Vallabhaneni S, Baker GJ, Schapiro D, et al.antibodies (MAB3581, AF231, MAB1129, and MAB3481, respectively), biotinylated detection antibodies (BAF358, BAF231, BAF1129, and BAM348, respectively) and recombinant proteins used for quantification (8614-MT,

(3) Induction of MET Receptor Tyrosine Kinase Down-regulation through Antibody-mediated Receptor ClusteringScientific reportsFebruary 13, 2019Li W, Dick A, Lu F, Zhang H, Sun H.

(4) Systems Modeling Identifies Divergent Receptor Tyrosine Kinase Reprogramming to MAPK Pathway InhibitionCellular and molecular bioengineeringJanuary 1, 2018Claas AM, Atta L, Gordonov S, Meyer AS, Lauffenburger DA.Biotinylated detection antibodies for Axl, Met, EGFR and Her2 were purchased from R&D Systems (BAF154, BAF358, BAF231, and BAF1129 respectively). Streptavidin Phycoerythrin (SAPE) was purchased from Biorad (cat.

(5) Tumor and Plasma Met Levels in Non-Metastatic Prostate CancerPloS oneJanuary 1, 2016Kaye DR, Pinto PA, Cecchi F, Reilly J, Semerjian A, Rabe DC, Gupta G, Choyke PL, Bottaro DP.and coated with a biotin-tagged, affinity-purified human Met ectodomain-specific capture antibody (BAF358, R&D Systems). Wells were washed again before adding sample or sMet standard (358-MT, R&D Systems) for

(6) Preliminary evaluation of urinary soluble Met as a biomarker for urothelial carcinoma of the bladderJournal of translational medicineOctober 21, 2014McNeil BK, Sorbellini M, Grubb RL 3rd, Apolo A, Cecchi F, Athauda G, Cohen B, Giubellino A, Simpson H, Agarwal PK, et al.PBS and coated with a biotin-tagged, affinitypurified human Met ectodomain-specific capture antibody (BAF358, R&D Systems). Wells were washed again before adding sample or sMet standard (358-MT, R&D Systems) for

(7) The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signalingMolecular and cellular biologyJuly 1, 2014Cen B, Xiong Y, Song JH, Mahajan S, DuPont R, McEachern K, DeAngelo DJ, Cortes JE, Minden MD, Ebens A, et al.antibodies were purchased from Santa Cruz Biotechnology. Biotinylated anti-MET antibody (catalog no. BAF358), for detecting MET in AML cell lines and patient samples, was from R&D Systems. Anti-Bcl-2 antibody

(8) A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastasesClinical cancer research : an official journal of the American Association for Cancer ResearchMay 15, 2014Tabernero J, Elez ME, Herranz M, Rico I, Prudkin L, Andreu J, Mateos J, Carreras MJ, Han M, Gifford J, et al.

(9) Safety, pharmacokinetics, and pharmacodynamics of AMG 102, a fully human hepatocyte growth factor-neutralizing monoclonal antibody, in a first-in-human study of patients with advanced solid tumorsClinical cancer research : an official journal of the American Association for Cancer ResearchJanuary 15, 2010Gordon MS, Sweeney CS, Mendelson DS, Eckhardt SG, Anderson A, Beaupre DM, Branstetter D, Burgess TL, Coxon A, Deng H, et al.

(10) Soluble c-Met receptors inhibit phosphorylation of c-Met and growth of hepatocyte growth factor: c-Met-dependent tumors in animal modelsMolecular cancer therapeuticsMay 1, 2009Coxon A, Rex K, Meyer S, Sun J, Sun J, Chen Q, Radinsky R, Kendall R, Burgess TL.

(11) Identificaiton of Shc Src Homology 2 Domain-Binding Peptoid – Peptide HybridsJournal of Medicinal ChemistryMarch 26, 2009Won Jun Choi et al.and phosphatase inhibitors. After incubation with a biotin-tagged, affinity-purified c-Met antibody (BAF358, R&D Systems, Minneapolis, MN; 1 h on ice), immunocomplexes were captured using a streptavidin resin

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HGFR/c-MET Biotinylated Antibody

HGFR/c-MET Biotinylated Antibody

Human HGFR/c-MET Biotinylated Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (11)

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Human HGFR/c-MET Biotinylated Antibody from R&D Systems, a Bio-Techne Brand

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