aggrecan/brevican (D-4) Antibody sc-166951 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemaggrecan/brevican (D-4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-166951
ApplicationsWB, IP, IF, ELISA
Hostmouse
NCBI Gene AliasesBEHAB, CSPG1, CSPG7, SSOAOD, CSPGCP, MSK16, AGC1, AGCAN, SEDK
Quantity200 µg/ml
CloneD-4
Antibody TypePrimary Antibodies
ClonalityMonoclonal
Reactivitymouse, rat, human
FormatPurified
Conjugate/TagUnconjugated
NCBI Full Gene Namebrevican, aggrecan
Targetaggrecan/brevican
IsotypeIgM

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Synovial mesenchymal stem cell-derived exosomal miR-485-3p relieves cartilage damage in osteoarthritis by targeting the NRP1-mediated PI3K/Akt pathway: Exosomal miR-485-3p relieves cartilage damageHeliyonJanuary 30, 2024Mingjun Qiu, Yanhua Xie, Guanghua Tan, Xiaoxu Wang, Peiguan Huang, Liang Hongagainst CD81 (ab109201, 1:1000, Abcam), TSG101 (bsm-52746R, 1:500, Bioss, Beijing, China), Aggrecan (sc-166951, 1:500, Santa Cruz, USA), Collagen II (bs-11929R, 1:1000, Bioss), MMP13 (bs-10581R, 1:500, Bioss), NRP1

(2) Plastrum testudinis Ameliorates Oxidative Stress in Nucleus Pulposus Cells via Downregulating the TNF-α Signaling PathwayPharmaceuticals (Basel)October 17, 2023Peng Zhang, Jiahui He, Yanchi Gan, Qi Shang, Honglin Chen, Wenhua Zhao, Gengyang Shen, Xiaobing Jiang, Hui Ren(AF7014), and p16 (AF0228) antibodies were obtained from Affinity Biosciences (Cincinnati, OH, USA). ACAN (sc-166951) and COL2A1 (sc-52658) were from Santa Cruz (Shanghai, China), and prostaglandin G/H synthase 2 (PTGS2)

(3) Lepr-Expressing PDLSCs Contribute to Periodontal Homeostasis and Respond to Mechanical Force by Piezo1Advanced science (Weinheim, Baden-Wurttemberg, Germany)October 1, 2023Zhang D, Lin W, Jiang S, Deng P, Liu L, Wang Q, Sheng R, Shu HS, Wang L, Zou W, et al.rabbit‐anti‐Osterix(1:300, ab22552, Abcam), rabbit‐anti‐perilipin(1:800, ab3526, Abcam), mouse‐anti‐Aggrecan(1:200, sc‐166951, Santa cruz), rabbit‐anti‐PIEZO1(1:200, NBP1‐78446, Novus). Donkey anti‐goat Alexa Fluor 647(1:200,

(4) Hypoxia regulates adipose mesenchymal stem cells proliferation, migration, and nucleus pulposus-like differentiation by regulating endoplasmic reticulum stress via the HIF-1α pathwayJournal of orthopaedic surgery and researchMay 8, 2023Wu J, Yu L, Liu Y, Xiao B, Ye X, Zhao H, Xi Y, Shi Z, Wang W.following: HIF-1α (ab8366, Abcam, USA), collagen II (GB11021, Servicebio, Wuhan, China), aggrecan (sc166951, Santa Cruz, Dallas, TX, USA), sox9 (ab185966, Abcam, USA), CHOP(2895,CST), ATF6 (1-40,256, NBP), and

(5) Bardoxolone methyl ameliorates osteoarthritis by inhibiting osteoclastogenesis and protecting the extracellular matrix against degradationHeliyonFebruary 1, 2023Yang R, Guo Y, Zong S, Ma Z, Wang Z, Zhao J, Yang J, Li L, Chen C, Wang S.

(6) Endothelial PDGF-BB/PDGFR-β signaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formationBone researchAugust 29, 2022Cui Z, Wu H, Xiao Y, Xu T, Jia J, Lin H, Lin R, Chen K, Lin Y, Li K, et al.ATAMDTS (Santa Cruz, 1:200, #C04789), SOX9 (Santa Cruz, 1:50, sc-166505), Aggrecan (Santa Cruz, 1:50, sc-166951), and COL II (Santa Cruz, 1:50, sc-52658) at 4 °C overnight. Secondary antibodies conjugated with fluorescence

(7) Hypoxia-inducible factor expression is related to apoptosis and cartilage degradation in temporomandibular joint osteoarthritisBMC musculoskeletal disordersJune 16, 2022Zhang J, Hu Y, Wang Z, Wu X, Yang C, Yang H.temperature. The sections were incubated overnight at 4 °C with the primary antibodies against Aggrecan (Acan, sc-166951,Santa Cruz Biotechnology, 1:100, USA); type collagen II (Col II, ab34712, Abcam, 1:100, UK); ADAM metallopeptidase

(8) miR-29b inhibits TGF-β1-induced cell proliferation in articular chondrocytesBiochemistry and biophysics reportsMarch 1, 2022Horita M, Hsu SN, Raper A, Farquharson C, Stephen LA.sc-7764, Santa Cruz Biotechnology), a mouse monoclonal antibody against aggrecan (1:1000 dilution; sc-166951, Santa Cruz Biotechnology), and a rabbit monoclonal antibody against β-actin (1:1000 dilution; 4970,

(9) Genipin Cross-Linked Decellularized Nucleus Pulposus Hydrogel-Like Cell Delivery System Induces Differentiation of ADSCs and Retards Intervertebral Disc DegenerationFrontiers in bioengineering and biotechnologyJanuary 1, 2021Yu L, Liu Y, Wu J, Wang S, Yu J, Wang W, Ye X.(ab260043, Abcam, Cambridge, MA, USA) (ab205718); collagen II (GB11021, Servicebio, Wuhan, China); aggrecan (sc166951, Santa Cruz, Dallas, TX, USA); sox9 (ab185966, Abcam, USA); and GAPDH (ab8245). Then, the membranes

(10) Chondrogenic Potential of Human Dental Pulp Stem Cells Cultured as MicrotissuesStem cells internationalJanuary 1, 2021Salvador-Clavell R, Martín de Llano JJ, Milián L, Oliver M, Mata M, Carda C, Sancho-Tello M.rinsed with PBS, and immunofluorescence was carried out. Specific mouse IgG anti-human antibodies (sc-166951, aggrecan, Santa Cruz Biotechnology, dilution 1 : 200; C2456, type I collagen, Sigma, dilution 1 : 100;

(11) Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral boneJournal of orthopaedic translationSeptember 1, 2020Hu Y, Wu H, Xu T, Wang Y, Qin H, Yao Z, Chen P, Xie Y, Ji Z, Yang K, et al.Cambridge, UK), Col Ⅱ (1:50, sc-52658, Santa Cruz, Biotechnology, Heidelberg, Germany), aggrecan (1:50, sc-166951, Santa Cruz, Biotechnology, Heidelberg, Germany) and ADAMTS5 (1:100,#C04789, SAB, Baltimore, USA) at

(12) Salidroside Alleviates Cartilage Degeneration Through NF-κB Pathway in Osteoarthritis RatsDrug design, development and therapyJanuary 1, 2020Gao H, Peng L, Li C, Ji Q, Li P.

(13) Ulipristal Acetate Mediates Decreased Proteoglycan Expression Through Regulation of Nuclear Factor of Activated T-Cells (NFAT5)Reproductive sciences (Thousand Oaks, Calif.)February 1, 2019Britten JL, Malik M, Lewis TD, Catherino WH.milk in 0.1% Tween 20 in 1 TBS), membranes were washed and exposed to primary antibody against BCAN (sc-166951; 1:400; Santa Cruz Biotechnology), B3GAT1 (1:500; sc-390475), aldo-keto reductase family 1 member B1 (AKR1B1;

(14) Local intra‑articular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis modelMolecular medicine reportsMay 1, 2018Deng S, Zhou JL, Peng H, Fang HS, Liu F, Weng JQ.Mouse anti-collagen II monoclonal antibody (sc-52658) and rabbit anti-aggrecan polyclonal antibody (sc-166951) were purchased from Santa Cruz Biotechnology. Inc. (Dallas, TX, USA); rabbit anti-MMP-3 polyclonal

(15) Perineuronal Net Protein Neurocan Inhibits NCAM/EphA3 Repellent Signaling in GABAergic InterneuronsScientific reportsApril 18, 2018Sullivan CS, Gotthard I, Wyatt EV, Bongu S, Mohan V, Weinberg RJ, Maness PF.R&D) and PSA (Ab5324, Millipore). An antibody recognizing a shared epitope of aggrecan and brevican (sc-166951, Santa Cruz Biotechnology) was also used. Polyclonal antibodies were against neurocan (AF5800, R&D),

(16) Alterations of overused supraspinatus tendon: a possible role of glycosaminoglycans and HARP/pleiotrophin in early tendon pathologyJournal of orthopaedic research : official publication of the Orthopaedic Research SocietyJanuary 1, 2012Attia M, Scott A, Duchesnay A, Carpentier G, Soslowsky LJ, Huynh MB, Van Kuppevelt TH, Gossard C, Courty J, Tassoni MC, et al.

(17) Resveratrol Inhibition of the WNT/β-Catenin Pathway following Discogenic Low Back PainInternational journal of molecular sciencesJanuary 1, 0001Genovese T, Impellizzeri D, D'Amico R, Cordaro M, Peritore AF, Crupi R, Gugliandolo E, Cuzzocrea S, Fusco R, Siracusa R, et al.The samples were stored at −80 °C for further analysis. Specific primary antibodies against Aggrecan (sc-166951, Santa Cruz Biotechnology), NGF (MA5-32067, Thermo Fisher, Milan, Italy), trkA (JJ084-04, Thermo Fisher),

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aggrecan/brevican (D-4) Antibody

aggrecan/brevican (D-4) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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aggrecan/brevican (D-4) Antibody from Santa Cruz Biotechnology, Inc.

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