Human IL-12 Rß1 Antibody AF839 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman IL-12 Rß1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF839
NCBI Gene AliasesIL12RB, CD212, IMD30, IL-12R-BETA1
ApplicationsFlow Cytometry,Western Blot,Neutralization
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
IsotypeIgG
Conjugate/TagUnconjugated
ReactivityHuman,Mouse
TargetIL-12 R beta 1
NCBI Full Gene Nameinterleukin 12 receptor subunit beta 1
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human IL-12 Rß1, Cys24-Glu540, Accession # P42701
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Questions and Answers

Can this antibody be used for detecting IL-12 R beta 1 in human samples?

Yes, the IL-12 R beta 1 Antibody has been shown to effectively detect human IL-12 R beta 1 in direct ELISAs and Western blots.

How specific is this antibody when used with mouse samples?

The antibody exhibits less than 2% cross-reactivity with recombinant mouse IL-12 R beta 1, indicating a high level of specificity for human samples.

What is the recommended storage condition for this antibody after reconstitution?

After reconstitution, the antibody should be stored under sterile conditions at -20 to -70 °C for up to 6 months, or at 2 to 8 °C for up to 1 month.

In what types of experiments has this antibody been cited?

The IL-12 R beta 1 Antibody has been cited in three scientific articles, indicating its utility in various research contexts, although specific applications are not detailed in the provided information.

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor beta 1Journal of immunology (Baltimore, Md. : 1950)December 15, 2003Russell TD, Yan Q, Fan G, Khalifah AP, Bishop DK, Brody SL, Walter MJ.incubated with goat IgG or goat anti-human IL-12R␤1 pAb with cross-reactivity to mice (catalogue no. AF839, 1 ␮g/ml; R&D Systems) for 15 min at 27°C, and the cells were then placed in the upper compartment of

(2) A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23RJournal of immunology (Baltimore, Md. : 1950)June 1, 2002Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, et al.

(3) Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12ImmunityNovember 1, 2000Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, et al.

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Human IL-12 Rß1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

Questions and Answers

R&D Systems, a Bio-Techne Brand

Citations (3)

Reviews

Human IL-12 Rß1 Antibody from R&D Systems, a Bio-Techne Brand

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