CD6 Antibody AF750 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCD6 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $349.00Supplier Page View Company Product Page
Catalog NumberAF750
ApplicationsFlow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Adhesion Blockade
ReactivityHuman,Mouse
IsotypeIgG
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
TargetCD6
HostGoat
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse CD6, Leu18-Gly396, Accession # Q91WN5
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene NameCD6 molecule
NCBI Gene AliasesTP120

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse CD6 in direct ELISAs and Western blots. In Western blots, approximately 1% cross-reactivity with recombinant human CD6 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A skeletal muscle atlas shows neuromuscular junction adaptations to growth and atrophyDev CellApril 21, 2026Silvia Campanario, Mercedes Grima-Terrén, Megan Rommelfanger, Stefania Dell' Orso, Xuesong Feng, Andrés Cisneros, Ignacio Ramírez-Pardo, Aina Calls-Cobos, Benjamin A. Yang, Kyung Dae Ko, et al.,Sigma Aldrich,Cat# HPA023370 AF647 Rabbit anti-Laminin (dilution 1:200),Novus biologicals,Cat# NB300-144AF647 AF750 Rabbit anti-Laminin (dilution 1:100),Novus biologicals,Cat# NB300-144AF750 Rabbit anti-Ki67 (dilution

(2) Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunityNatureMarch 25, 2026Sam O. Kleeman, Kevin Michalski, Xiang Zhao, Ruben Steigerwald, Miriam Ferrer, Llewelyn Levett, Ethan Ertel, Austin Schultz, Noriko Simorowski, Pamela Moody, et al.Alexa Fluor 647 anti-mouse CD3 (100209, BioLegend), 1:100 dilution; and Alexa Fluor 750 anti-pan-cytokeratin (NBP1-48348-AF750, Novus Biologicals), 1:200 dilution. Quantification and statistical analysis Data are expressed as

(3) Functional Type I and Type II interferon crosstalk restricts progenitor exhausted CD8 T cells through spatial exclusion and checkpoint enforcementbioRxivMarch 3, 2026Siran Liu, Heidi J. Elsaesser, Rene Quevedo, Diala Abd-Rabbo, Bruna C. Bertol, Wenxi Xu, Melissa Yi Ran Liu, Sabelo Lukhele, Sara Lamorte, Tracy L. McGaha, et al.Biolegend), CD45.1-biotin(A20, Biolgend), rabbit-anti-TCF1(C63D9, Cell Signaling Technology), B220-AF750(RA3–6B2, R&D System); chicken-anti-GFP(Polyclonal, ab13970, Abcam), CD45.2-biotin(104, Biolegend), CD4-AF647(RM4–5,

(4) A Multimodal Imaging Pipeline for the Discovery of Molecular Markers of Cellular NeighborhoodsbioRxivFebruary 17, 2026Thai Pham, Melissa A. Farrow, Lukasz G. Migas, Martin Dufresne, Madeline E. Colley, Jamie L. Allen, Angela R.S. Kruse, Mark P. de Caestecker, Raf Van de Plas, Jeffrey M. SpragginsT Cell,BX025,RX025,AF750,2 CD31,Akoya,SKU 4250009,Endothelial Cell (ECs),BX032,RX032,ATTO550,3 CD20,Abcam,ab236434,B Cell,BX028,RX028,AF750,3 LYVE-1,R&D System,R&D AF2089,Lymphatic Vessel ECs,BX017,RX017,ATTO550,4 CD3,Abcam,ab245731,T Cell,BX010,RX010,AF750,4 Laminin

(5) Explainable AI-based analysis of human pancreas sections identifies traits of type 2 diabetesNat CommunFebruary 9, 2026Lukas Klein, Sebastian Ziegler, Felicia Gerst, Yanni Morgenroth, Karol Gotkowski, Eyke Schöniger, Martin Heni, Nicole Kipke, Daniela Friedland, Annika Seiler, et al.IgG2a con. AF647 (1:50; Invitrogen, #A21241), and for the third incubation against somatostatin con. AF750 (1:200; Novus Biologicals, #NBP2-99309 AF750) with DAPI (1 ng/ml; Invitrogen, #D1306). The cocktails

(6) Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunityImmunityJanuary 13, 2026Beatrice Zitti, Florent Duval, Pratyaksha Wirapati, Mehdi Hicham, Yuxuan Xie, Juhyun Oh, Jan Hoelzl, Philippa Meiser, Marco Varrone, Hannah M. Peterson, et al.,Novus Biologicals,Cat# NB100-77673SS AF555 rabbit anti-human CD45 (Clone AKYP0074),Akoya Biosciences,Cat#240060 AF750 mouse anti-human panCK (Clone AKYP0053),Akoya Biosciences,Cat#S6501000 AF647 rabbit anti-human CD4

(7) Hepatitis C virus modified (S)E2(F442NYT)-mRNA-LNP candidate vaccine promotes helper CXCR5(+)T cellsJournal of virologyOctober 23, 2025Haga Y, Babu E P, Swiderska-Syn M, Reagan EK, Weissman D, Ray R.R&D Systems,Novus,NBP2-75460 Donkey anti-rabbit IgG AF488 (min x reactivity),Biolegend,406416 Rat anti-mouse CD3 (17A2) AF750,R&D Systems,FAB4841RS10 Rb anti-rat IgG H&L biotinylated,Vector Lab,BA-4001 SA-PE 0.2 mg/mL,Biolegend

(8) Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanomaNature CommunicationsSeptember 1, 2025Jiekun Yang, Cassia Wang, Doris Fu, Li-Lun Ho, Kyriakitsa Galani, Lee Chen, Jose Gonzalez, Jolene Fu, Amy Y. Huang, Dennie T. Frederick, et al.polyclonal goat anti-human IRF8 (1:200, Novus Bio) antibodies overnight at 4 °C followed by goat anti-rabbit AF750 (1:2000, Thermo), goat anti-armenian hamster AF488 (1:1000, Thermo), goat anti-mouse IgG2a AF594 (1:2000,

(9) Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosisNature AgingJune 30, 2025Roméo S. Blanc, Nidhi Shah, Sarah Hachmer, Noah A. S. Salama, Fanju W. Meng, Alireza Mousaei, Gayatri Puri, Jeonghye Hannah Hwang, Elizabeth E. Wacker, Benjamin A. Yang, et al.(Cell Signaling Technology, 9718); mouse anti-γH2AX(Ser139) (Millipore, 05–636); rabbit anti-γH2AX(S139)[-AF750] (BioTechne, IC2288); rabbit anti-pP53(Ser15) (Cell Signaling Technology, 9284); rabbit anti-pP53(Ser46)

(10) Protective Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles on Inner Ear Sensorineural Cells Affected by CisplatinMedicina (Kaunas)June 5, 2025Maria Perde-Schrepler, Ioana Brie, Mihai Cenariu, Sergiu Chira, Lajos Raduly, Liviuta Budisan, Ioana Berindan-Neagoe, Rares Stiufiuc, Maximilian Dindelegan, Cristina Blebea, et al.Franklin Lakes, NJ, USA). We used fluorescently conjugated antibodies: mouse anti-CD73 conjugated with AF750, anti-CD105 conjugated with FITC, anti-CD90 conjugated with PE, and anti-CD34. All antibodies were from

(11) Activation of lysosomal iron triggers ferroptosis in cancerNatureJune 1, 2025Cañeque T, Baron L, Müller S, Carmona A, Colombeau L, Versini A, Solier S, Gaillet C, Sindikubwabo F, Sampaio JL, et al.manufacturer); FAP-AF700 (R&D Systems, FAB3715N, clone 427819, lot AEVI020011, FCy, 1:100, Hu); FAP-AF750 (Bio-Techne, FAB3715S-100UG, clone 427819, lot 1718688, FCy, 1:100, Hu); ferritin (Abcam, ab75973, clone

(12) Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastomaNature medicineMay 1, 2025Long GV, Shklovskaya E, Satgunaseelan L, Mao Y, da Silva IP, Perry KA, Diefenbach RJ, Gide TN, Shivalingam B, Buckland ME, et al.(AF488; cat. no. 560297, Becton Dickinson), anti-EGFR (PE; cat. no. FAB9577P, R&D Systems), anti-CD45 (AF750; cat. no. NBP1-79127AF750, Novus Biologicals), anti-CD66b (AF750; cat. no. FAB42462, R&D Systems) antibodies

(13) Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistributionNature communicationsFebruary 20, 2025Khoury N, Pizzo ME, Discenza CB, Joy D, Tatarakis D, Todorov MI, Negwer M, Ha C, De Melo GL, Sarrafha L, et al.(Jackson Immunoresearch, 709-606-149 lot 168098), aSMA alpha-Smooth Muscle Actin Antibody (1A4/asm-1) AF750 (Novus Biological NBP2-33006AF750 lot D149482), Caveolin-1 (Cell Signaling 3267S lot 9, 1:500), and

(14) Characterizing SV40-hTERT Immortalized Human Lung Microvascular Endothelial Cells as Model System for Mechanical Stretch-Induced Lung InjuryInternational journal of molecular sciencesJanuary 15, 2025Hochreiter B, Lindner C, Postl M, Hunyadi-Gulyas E, Darula Z, Domenig O, Sharma S, Lang IM, Kiss A, Spittler A, et al.Lynnwood, WA, USA), anti-human ACE-PE/Cy7 (Biolegend, St. Diego, CA, USA, clone 5–369), anti-human ACE2-AF750 (R&D Systems, Minneapolis, MI, USA; clone 535919)) were centrifuged for 10 min at 17,000× g. A total

(15) CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infectionsPLOS PathogensNovember 4, 2024Tyler B. Rollman, Zachary W. Berkebile, Dustin M. Hicks, Jason S. Hatfield, Priyanka Chauhan, Marco Pravetoni, Mark R. Schleiss, Gregg N. Milligan, Terry K. Morgan, Craig J. Bierlethe dark. Cocktails of antibodies were prepared (α-PanT Lymphocytes:APC [Bio-Rad, MCA751APC], α-CD45:AF750 [Bio-Techne, NB100-65362AF750], α-CD4:PE [Bio-Rad, MCA749PE], α-CD8:FITC [Bio-Rad, MCA752F], α-CD14:

(16) Targeting Tumor-Associated Macrophages with the Immune-Activating Nanomedicine for Achieving Strong Antitumor Activity with Rapid Clearance from the BodyACS NanoAugust 27, 2024Yosuke Ota, Ryosaku Inagaki, Yosuke Takanashi, Hiro Uemachi, Kimiya Matsuda, Makoto Matsuoka, Risa Taoda, Seina Ohe, Yukari Ishitsubo, Megumi Nakamura, et al.IL-10 (R and D Systems, 20 ng/mL) for 2 days in the growth medium. Then, the cells were incubated with AF750-5 kDa dextran (1 μg/mL) for 1 h, and uptake was analyzed as described above. CD206 expression was confirmed

(17) Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patientsCancer cellMarch 11, 2024Radtke AJ, Postovalova E, Varlamova A, Bagaev A, Sorokina M, Kudryashova O, Meerson M, Polyakova M, Galkin I, Svekolkin V, et al.AB_2650712 Ki-67 Biotin (polyclonal),Novus Biologicals,Cat# NB500-170B; RRID: AB_1660247 Streptavidin AF750,Thermo Fisher Scientific,Cat#S21384; RRID: N/A Desmin AF488 (clone DES/1711),Novus Biologicals,Cat#NBP2-54503AF488;

(18) The Proteome of Extracellular Vesicles Released from Pulmonary Microvascular Endothelium Reveals Impact of Oxygen Conditions on BiotraumaInternational journal of molecular sciencesFebruary 19, 2024Schaubmayr W, Hochreiter B, Hunyadi-Gulyas E, Riegler L, Schmidt K, Tiboldi A, Moser B, Klein KU, Krenn K, Scharbert G, et al.(LSBio: LS-C751060), anti-human ACE-PE/Cy7 (Biolegend, San Diego, CA, USA #344208), and anti-human ACE2-AF750 (R&D Systems, Minneapolis, MN, USA; #AB9332). A total of 25 μL PBS was added to 10 μL concentrated vesicle

(19) Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironmentsCell & bioscienceFebruary 4, 2024Abraham MJ, Goncalves C, McCallum P, Gupta V, Preston SEJ, Huang F, Chou H, Gagnon N, Johnson NA, Miller WH, et al.,Cell Signaling,D4V4B,86916SF,BX027,RX027-AF647 CD31,Dianova,SZ31,DIA-310-BA-2,BX026,RX026-ATT0550 CD45,R&D Systems,Polyclonal,AF114-SP,BX007,RX007-AF750 c-Myc,Abcam,Y69,ab168727,BX001,RX001-AF750 F4/80,Cell Signaling,D2S9R,25514SF,BX020,RX020-ATTO550 FoxP3,Cell Signaling

(20) Polyinosinic: polycytidylic acid induced inflammation enhances while lipopolysaccharide diminishes alloimmunity to platelet transfusion in miceFront ImmunolDecember 11, 2023Johnson Q. Tran, Marcus O. Muench, Betty Gaillard, Orsolya Darst, Mary M. Tomayko, Rachael P. JackmanCD23-BUV395 (B3B4) and IgD-BUV496 (AMS9.1) (BD); B220-AF532 (RM0063-9F14, Novus Biologicals); and CD73-AF750 (496406, R&D Systems). To exclude non-B cells, the following AF700 conjugated anti-mouse antibodies

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CD6 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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CD6 Antibody from R&D Systems, a Bio-Techne Brand

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