Human TRAIL R3/TNFRSF10C Antibody AF630 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman TRAIL R3/TNFRSF10C Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF630
Quantity100 ug (also 25 ug)
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Neutralization,Immunocytochemistry,Cell Culture
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ConcentrationLYOPH
PurityAntigen Affinity-purified
IsotypeIgG
ReactivityHuman
TargetTRAIL R3/TNFRSF10C
HostGoat
Antibody TypePrimary Antibodies
NCBI Gene AliasesDCR1, TRID, CD263, LIT, DCR1-TNFR, TRAIL-R3, TRAILR3
NCBI Full Gene NameTNF receptor superfamily member 10c
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human TRAIL R3/TNFRSF10C, Ala26-Ala221, Accession # O14798
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cellsEMBO reportsAugust 3, 2022Höfle J, Trenkner T, Kleist N, Schwane V, Vollmers S, Barcelona B, Niehrs A, Fittje P, Huynh-Tran VH, Sauter J, et al.,Miltenyi Biotec,Cat#130‐097‐303; RRID:AB_2656745 "α‐human TRAIL‐R3 (DcR1, CD263) (polyclonal Goat IgG)",R&D Systems,Cat#AF630; RRID:AB_355488 Mouse α‐human CD314 (NKG2D) (clone 1D11),BioLegend,Cat#320814; RRID:AB_2561488 Mouse

(2) Cytotoxic Efficacy and Resistance Mechanism of a TRAIL and VEGFA-Peptide Fusion Protein in Colorectal Cancer ModelsInternational journal of molecular sciencesMarch 19, 2021Kopczynski M, Statkiewicz M, Cybulska M, Kuklinska U, Unrug-Bielawska K, Sandowska-Markiewicz Z, Grochowska A, Gajewska M, Kulecka M, Ostrowski J, et al.R&D Systems, Minneapolis, MN, USA), TNFRSF10B (AF631, R&D Systems, Minneapolis, MN, USA), TNFRSF10C (AF630, R&D Systems, Minneapolis, MN, USA), and TNFRSF10D (AF633, R&D Systems, Minneapolis, MN, USA). Cells

(3) Chemotherapeutic Agents Sensitize Resistant Cancer Cells to the DR5-Specific Variant DR5-B more Efficiently than to TRAIL by Modulating the Surface Expression of Death and Decoy ReceptorsCancersApril 30, 2020Аrtykov АА, Belov DA, Shipunova VO, Trushina DB, Deyev SM, Dolgikh DA, Kirpichnikov MP, Gasparian ME.panobinostat and bortezomib were from Santa Cruz (Dallas, TX, USA). Antibodies to decoy receptors DcR1 (AF630) and to DcR2 (AF633) were form R&D systems. 4.2. Expression and Purification of Recombinant Preparations

(4) Resistance to TRAIL in non-transformed cells is due to multiple redundant pathwaysCell death & diseaseJuly 4, 2013van Dijk M, Halpin-McCormick A, Sessler T, Samali A, Szegezdi E.TRAIL-R2 (ALX-804-298-C100; Enzo Life Sciences) or goat polyclonal antibodies against TRAIL R3/TNFRSF10C (AF630) or TRAIL R4/TNFRSF10D antibodies (AF633; R&D Systems, Minneapolis, MN, USA) for 1 h on ice followed

(5) PTHrP Overexpression Increases Sensitivity of Breast Cancer Cells to Apo2L/TRAILPLoS ONEJune 18, 2013Vanessa Cheung, Steve Bouralexis, Matthew T. Gillespieantibodies against human Apo2L/TRAIL-R1/DR4 (AF347), Apo2L/TRAIL-R2/DR5 (AF631), Apo2L/TRAIL-R3/DcR1 (AF630), Apo2L/TRAIL-R4 (AF633), mouse IgG2B (MAB004), mouse IgG1 (MAB002), monoclonal antihuman Caspase-7

(6) TRAIL recombinant adenovirus triggers robust apoptosis in multidrug-resistant HL-60/Vinc cells preferentially through death receptor DR5Human gene therapyJuly 1, 2008Wu CH, Kao CH, Safa AR.

(7) Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivoInternational journal of oncologyDecember 1, 2007Zopf S, Neureiter D, Bouralexis S, Abt T, Glaser KB, Okamoto K, Ganslmayer M, Hahn EG, Herold C, Ocker M.

(8) P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5Biochemical pharmacologyJuly 28, 2006Park SJ, Wu CH, Choi MR, Najafi F, Emami A, Safa AR.

(9) Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3Molecular cancer therapeuticsMarch 1, 2006Lane D, Côté M, Grondin R, Couture MC, Piché A.

(10) Death receptors, Fas and TRAIL receptors, are involved in human osteoclast apoptosisBiochemical and biophysical research communicationsJuly 22, 2005Roux S, Lambert-Comeau P, Saint-Pierre C, Lépine M, Sawan B, Parent JL.

(11) Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cellsCirculation researchApril 18, 2003Zauli G, Pandolfi A, Gonelli A, Di Pietro R, Guarnieri S, Ciabattoni G, Rana R, Vitale M, Secchiero P.

(12) Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implicationsOncogeneAugust 22, 2002Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG, et al.

(13) Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cellsCell death and differentiationMarch 1, 2002Bretz JD, Mezosi E, Giordano TJ, Gauger PG, Thompson NW, Baker JR Jr.

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TRAIL R3/TNFRSF10C Antibody

TRAIL R3/TNFRSF10C Antibody

TRAIL R3/TNFRSF10C Antibody

TRAIL R3/TNFRSF10C Antibody

TRAIL R3/TNFRSF10C Antibody

Human TRAIL R3/TNFRSF10C Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

Reviews

Human TRAIL R3/TNFRSF10C Antibody from R&D Systems, a Bio-Techne Brand

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