IL-4R alpha Antibody AF530 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-4R alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF530
ApplicationsFlow Cytometry,Western Blot,Neutralization,Immunocytochemistry,CyTOF-ready
Conjugate/TagUnconjugated
IsotypeIgG
ReactivityMouse
HostGoat
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
TargetIL-4R alpha
ClonalityPolyclonal
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameinterleukin 4 receptor
NCBI Gene AliasesCD124, IL-4RA, IL4RA
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse IL-4 R alpha

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse IL-4 R alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) IL-4 R, rhIL-9 R, rhIL-13 R alpha 1, and recombinant mouse IL-13 R alpha 2 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasisTheranosticsJanuary 1, 2024Vadevoo SMP, Kang Y, Gunassekaran GR, Lee SM, Park MS, Jo DG, Kim SK, Lee H, Kim WJ, Lee B.

(2) IL-13 immunotoxin accelerates resolution of lung pathological changes triggered by silica particles in miceJournal of immunology (Baltimore, Md. : 1950)November 15, 2013Ferreira TP, de Arantes AC, do Nascimento CV, Olsen PC, Trentin PG, Rocco PR, Hogaboam CM, Puri RK, Martins MA, Silva PM.(a-smooth muscle actin), and F4/80. The Abs were obtained from the following sources: anti–IL-4Ra (AF530) and anti–IL-13Ra2 (AF539) from R&D Systems (Minneapolis, MN); anti–IL13Ra1 (849680) from Abcam (Cambridge,

(3) Shaping the murine macrophage phenotype: IL-4 and cyclic AMP synergistically activate the arginase I promoterJournal of immunology (Baltimore, Md. : 1950)September 1, 2013Sheldon KE, Shandilya H, Kepka-Lenhart D, Poljakovic M, Ghosh A, Morris SM Jr.nonfat milk in TBS. Immunoblots of whole cell lysates were probed with antibodies to IL-4Rα (1:500; cat #AF530, R&D Systems) and α-tubulin (1:10,000; Cat#ab7291, Abcam), with antibodies to STAT6 (1:2000; ) cat#

(4) The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell developmentDevelopment (Cambridge, England)August 1, 2007Khaled WT, Read EK, Nicholson SE, Baxter FO, Brennan AJ, Came PJ, Sprigg N, McKenzie AN, Watson CJ.

(5) Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblastsThe American journal of pathologyMay 1, 2003Jakubzick C, Choi ES, Kunkel SL, Joshi BH, Puri RK, Hogaboam CM.

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Mouse IL-4R alpha Antibody

IL-4R alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (5)

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IL-4R alpha Antibody from R&D Systems, a Bio-Techne Brand

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