Bcl-2 Antibody AF810 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemBcl-2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF810
ApplicationsBioassay,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Simple Western
ReactivityHuman,Mouse
HostGoat
TargetBcl-2
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant mouse Bcl-2
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene NameBCL2 apoptosis regulator
NCBI Gene AliasesBcl-2, PPP1R50

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human and mouse Bcl-2 in Western blots.

Sizes Available: 100 ug (also 25 ug)

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Development of Biphenyl-Substituted Uracil-Based Hydroxamic Acids (UBHAs) as Potent HDAC Inhibitors with Pro-Apoptotic Activity in Leukemia and Prostate Cancer CellsJournal of Medicinal ChemistryMay 14, 2026Francesco Fiorentino, Giulio Bontempi, Federica Michetti, Valeria Pecci, Emanuele Fabbrizi, Daniela Passeri, Letizia Corsetti, Valentina Farini, Fabrizio Casano, Antimo Gioiello, et al.H3 (acetyl K9) abcam (#ab10812), Acetyl-α-Tubulin (Lys40) Invitrogen (#32-2700), Bcl-2 R&D system (#AF810), p21 WAF1/Cip1 (12D1) Cell Signaling (#2947), β-actin Abcam (#ab8227), Donkey anti-Goat IgG HRP Abcam

(2) Cellular senescence mediates doxorubicin chemotherapy-induced vascular endothelial dysfunction: translational evidence of prevention with senolytic treatmentAmerican Journal of Physiology-Heart and Circulatory PhysiologyDecember 1, 2025Ravinandan Venkatasubramanian, Sophia A. Mahoney, David A. Hutton, Nicholas S. VanDongen, Vienna E. Brunt, Nathan T. Greenberg, Abigail G. Longtine, Lukas Brandt, Andreas M. Beyer, Simon Melov, et al.Cell Signaling; Danvers, MA Cat. No. 2772), BCL-2 (anti-goat; 1:50; R&D Systems, Minneapolis, MN Cat. No. AF810); Manganese superoxide dismutase (SOD2) (antigoat; 1:50; R&D Systems, cat no. AF3419) were determined

(3) Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancerCancer cell internationalFebruary 5, 2024Pecci V, Troisi F, Aiello A, De Martino S, Carlino A, Fiorentino V, Ripoli C, Rotili D, Pierconti F, Martini M, et al.06-680, RRID:AB_310214), ARv7 (Precision antibody Cat# AG10008, RRID:AB_2631057), Bcl-2 (R&D Systems Cat# AF810, RRID:AB_355621; Cat# MAB8272, RRID:AB_10890789; Dako clone 124 Cat# M0887, RRID:AB_2064429), β4 integrin

(4) Targeting Cell Death Mechanism Specifically in Triple Negative Breast Cancer Cell LinesInternational journal of molecular sciencesApril 26, 2022Pruteanu LL, Braicu C, Módos D, Jurj MA, Raduly LZ, Zănoagă O, Magdo L, Cojocneanu R, Paşca S, Moldovan C, et al.

(5) Knockdown of lncRNA CCAT1 Inhibits the Progression of Colorectal Cancer via hsa-miR-4679 Mediating the Downregulation of GNG10Journal of immunology researchJanuary 1, 2021Wang N, Li J, He J, Jing YG, Zhao WD, Yu WJ, Wang J.caspase-3 (1 : 1000, ab2302, Abcam, USA); Bax (1 : 1000, MA5-35342, Thermo Fisher, USA); Bcl-2 (1 : 1000, AF810, R&D System, USA); and GAPDH (1 : 1500, ab8243, Abcam, USA). 2.6. Cell Migration and Invasion Assays HT-29 cells

(6) Interleukin-22 regulates gastric cancer cell proliferation through regulation of the JNK signaling pathwayExperimental and therapeutic medicineJuly 1, 2020Dong H, Zhu F, Jin S, Tian J.(AF1205; 1:500), anti‑STAT3 mab (MAB1799; 1:1,000), anti‑p‑STAT3 mab (AF4607; 1:500), anti‑Bcl‑2 mab (AF810; 1:1,000), anti‑GAPDH mab (MAB5718; 1:2,000) and mouse or rabbit horseradish peroxidase (HRP)‑conjugated secondary

(7) Influence mechanism of miRNA-144 on proliferation and apoptosis of osteosarcoma cellsOncology lettersFebruary 1, 2020Zhang X, Li Z, Ji W, Chen X, Gao Q, Li D, Qin H.Thermo Scientific), Bax, caspase-3, Bcl-2 HPR-labeled goat anti-mouse IgG secondary antibody (AF820, AF835, AF810; R&D Systems, Inc.), Annexin V/PI apoptosis detection kit (40302ES20; Shanghai Yu Sheng Biotechnology

(8) Lipid storage droplet protein 5 reduces sodium palmitate‑induced lipotoxicity in human normal liver cells by regulating lipid metabolism‑related factorsMolecular medicine reportsAugust 1, 2019Ma X, Cheng F, Yuan K, Jiang K, Zhu T.no. AF-605-NA; R&D Systems, Inc., Minneapolis, MN, USA), B-cell lymphoma-2 (Bcl-2; 1:800; cat. no. AF810; R&D Systems, Inc.), Bcl-2-associated X protein (Bax; 1:1,000; cat. no. AF820; R&D Systems, Inc.,),

(9) Genipin protects against H2O2-induced oxidative damage in retinal pigment epithelial cells by promoting Nrf2 signalingInternational journal of molecular medicineFebruary 1, 2019Zhao H, Wang R, Ye M, Zhang L.R&D Systems, Inc.), anti-cleaved-caspase-3 (AF835, 1:1,000; R&D Systems, Inc.), anti-B-cell lymphoma-2 (Bcl-2; AF810, 1:800; R&D Systems, Inc.), anti-Bcl-2 associated X (Bax; AF820, 1:1,000; R&D Systems, Inc.) and anti-GAPDH

(10) Protein Synthesis Inhibition Activity of Mesothelin Targeting Immunotoxin LMB-100 Decreases Concentrations of Oncogenic Signaling Molecules and Secreted Growth FactorsToxinsOctober 31, 2018El-Behaedi S, Landsman R, Rudloff M, Kolyvas E, Albalawy R, Zhang X, Bera T, Collins K, Kozlov S, Alewine C.blocked in 5% milk solution. The following antibodies were used: goat anti-human/mouse anti-Bcl-2 (AF810, R&D Systems, Minneapolis, MN, USA) and mouse anti-human anti-puromycin (MABE343, Millipore Sigma, St.

(11) B-cell lymphoma 2 is associated with advanced tumor grade and clinical stage, and reduced overall survival in young Chinese patients with colorectal carcinomaOncology lettersJune 1, 2018Wang J, He G, Yang Q, Bai L, Jian B, Li Q, Li Z.1:1,000), rabbit anti-p53 (cat. no. AF1355; R&D Systems Inc.; dilution, 1:2,000), mouse anti-Bcl-2 (cat no. AF810; R&D Systems Inc.; dilution, 1:1,000) and mouse anti-Ki-67/MIB-1 (cat no. AF7617; R&D Systems Inc.;

(12) TGF-β1 mediates the effects of aspirin on colonic tumor cell proliferation and apoptosisOncology lettersApril 1, 2018Wang Y, Du C, Zhang N, Li M, Liu Y, Zhao M, Wang F, Luo F.(1:1,000), including mouse‑anti‑β ‑actin (cat. no., MAB8929), rabbit‑anti‑B‑celllymphoma2 (Bcl‑2; cat. no., AF810), rabbit‑anti‑Bcl‑2‑associated X protein (Bax; cat. no., AF820), rabbit‑anti‑Caspase3 (cat. no., AF‑605‑NA; R&D Systems, Inc

(13) Securidaca-saponins are natural inhibitors of AKT, MCL-1, and BCL2L1 in cervical cancer cellsCancer management and researchJanuary 1, 2018Obasi TC, Braicu C, Iacob BC, Bodoki E, Jurj A, Raduly L, Oniga I, Berindan-Neagoe I, Oprean R.BCL-2 protein was assessed by immunostaining overnight with monoclonal BCL-2 primary antibody (10 µg/mL, AF810; R&D Systems, Inc., Minneapolis, MN, USA), followed by a washing step with phosphate-buffered saline

(14) TCDD promotes lung tumors via attenuation of apoptosis through activation of the Akt and ERK1/2 signaling pathwaysPloS oneJanuary 1, 2014Chen RJ, Siao SH, Hsu CH, Chang CY, Chang LW, Wu CH, Lin P, Wang YJ.

(15) Molecular profiling of cervical cancer progressionBritish journal of cancerJanuary 29, 2007Hagemann T, Bozanovic T, Hooper S, Ljubic A, Slettenaar VI, Wilson JL, Singh N, Gayther SA, Shepherd JH, Van Trappen PO.

(16) The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cellsThe Journal of biological chemistryJanuary 23, 2004Sade H, Krishna S, Sarin A.

Be the First to Write a Review!

Bcl-2 Antibody

Bcl-2 Antibody

Bcl-2 Antibody

Bcl-2 Antibody

Bcl-2 Antibody

Bcl-2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (16)

Reviews

Bcl-2 Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map