MMP-1 Antibody AF901 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMMP-1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberAF901
NCBI Gene AliasesCLGN, CLG
ApplicationsELISA Development,ELISA Microarray Development,Immunohistochemistry,Western Blot,Simple Western,ELISA Capture (Matched Antibody Pair)
HostGoat
IsotypeIgG
Conjugate/TagUnconjugated
ReactivityHuman
Quantity100 ug (also 25 ug)
NCBI Full Gene Namematrix metallopeptidase 1
ValidationKnockout Validated
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
PurityAntigen Affinity-purified
ConcentrationLYOPH
ImmunogenMouse myeloma cell line NS0-derived recombinant human MMP-1, Phe20-Asn469, Accession # P03956
ClonalityPolyclonal
TargetMMP-1
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human MMP-1 in ELISAs and Western blots. In sandwich immunoassays, less than 0.5% cross-reactivity with recombinant human (rh) MMP-2, rhMMP-3, rhMMP-7, rhMMP-8, rhMMP-9, rhMMP-10, rhMMP-12, rhMMP-13, and rhMMP-16 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to agingJCI insightJune 11, 2019Muñoz DP, Yannone SM, Daemen A, Sun Y, Vakar-Lopez F, Kawahara M, Freund AM, Rodier F, Wu JD, Desprez PY, et al.(R&D Systems, MAB2530), CD112 (Abcam, 502-57), DNAM-1 (R&D Systems, MAB666), IL-7 (Abcam, ab175380), MMP1 (R&D Systems, AF901; Oncogene Research Products, IM35L), MMP3 (R&D Systems, AF513; Oncogene Research Products, IM70T; BioVision,

(2) Overlooked benefits of using polyclonal antibodiesBioTechniquesSeptember 1, 2018Ascoli CA, Aggeler B.lysate was separated on a 4–20% SDS-PAGE, followed by western blot. Anti-human MMP1 goat polyclonal (AF901 from R&D Systems) used at 1 μg/ml is shown to detect both the recombinant protein control (lane 1),

(3) Protective effect of curcumin against ultraviolet A irradiation‑induced photoaging in human dermal fibroblastsMolecular medicine reportsMay 1, 2018Liu X, Zhang R, Shi H, Li X, Li Y, Taha A, Xu C.1:1,000) were purchased from Abcam (Cambridge, MA, USA). The antibody against MMP-1 (human, cat. no. AF901; 1:1,000) was purchased from Bio-Techne (Minneapolis, MN, USA). The antibody against Smad2/3 (rabbit;

(4) Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritisJournal of immunological methodsApril 30, 2012Zhao X, Qureshi F, Eastman PS, Manning WC, Alexander C, Robinson WH, Hesterberg LK.

(5) TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary diseaseThe Journal of biological chemistryAugust 26, 2011Geraghty P, Dabo AJ, D'Armiento J.

(6) Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunctionThe American journal of pathologyJanuary 1, 2011Estrada-Gutierrez G, Cappello RE, Mishra N, Romero R, Strauss JF 3rd, Walsh SW.

(7) Guggulsterone blocks IL-1beta-mediated inflammatory responses by suppressing NF-kappaB activation in fibroblast-like synoviocytesLife sciencesJune 6, 2008Lee YR, Lee JH, Noh EM, Kim EK, Song MY, Jung WS, Park SJ, Kim JS, Park JW, Kwon KB, et al.

(8) Development and validation of sandwich ELISA microarrays with minimal assay interferenceJournal of proteome researchJune 1, 2008Gonzalez RM, Seurynck-Servoss SL, Crowley SA, Brown M, Omenn GS, Hayes DF, Zangar RC.

(9) Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-alpha in human osteoarthritic chondrocytesFEBS lettersMay 1, 2007Nah SS, Choi IY, Yoo B, Kim YG, Moon HB, Lee CK.

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MMP-1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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MMP-1 Antibody from R&D Systems, a Bio-Techne Brand

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