Activin RIA/ALK-2 Antibody AF637 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemActivin RIA/ALK-2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF637
NCBI Gene AliasesACVR1A, ALK2, ACTRI, ACVRLK2, TSRI, SKR1, FOP
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,CyTOF-ready
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Rat
Quantity100 ug (also 25 ug)
TargetActivin RIA/ALK-2
IsotypeIgG
HostGoat
Conjugate/TagUnconjugated
NCBI Full Gene Nameactivin A receptor type 1
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human Activin RIA/ALK-2, Asp23-Glu123, Accession # Q04771
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human Activin RIA/ALK-2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Activin RIB, rhActivin RIIA, and rhActivin RIIB is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) BMP-2-Driven Osteogenesis: A Comparative Analysis of Porcine BMSCs and ASCs and the Role of TGF-β and FGF SignalingBiologyMay 26, 2025Taday R, Jungbluth P, Zensen S, Krakau T, Windolf J, Hoffmann MJ, Grotheer V.ALK6 (Cat. No.: FAB5051A), TGF-β2-RII (Cat. No.: FAB532P), ALK7 (Cat. No.: FAB77491A), ALK2 (Cat. No.: AF637), ALK4 (Cat. No.: MAB2221), and BMPR-II (Cat. No.: AF811) (by R&D Systems, Minneapolis, MN, USA), and

(2) An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva miceThe Journal of clinical investigationJune 15, 2022Lees-Shepard JB, Stoessel SJ, Chandler JT, Bouchard K, Bento P, Apuzzo LN, Devarakonda PM, Hunter JW, Goldhamer DJ.screened for ACVR1 or ALK3 protein expression by flow cytometry with an anti-ACVR1 antibody (R&D Systems, AF637) and an anti-ALK3 antibody (Sino Biological, 50078), respectively. Acvr1-KO and Alk3-KO clones were

(3) Growth Differentiation Factor-15 Produces Analgesia by Inhibiting Tetrodotoxin-Resistant Nav1.8 Sodium Channel Activity in Rat Primary Sensory NeuronsNeuroscience bulletinSeptember 1, 2021Lin W, Zhang WW, Lyu N, Cao H, Xu WD, Zhang YQ.RT, then overnight at 4°C with the following primary antibodies: goat anti-ALK2 (1:100, R&D Systems, AF637, 1291 Minneapolis, MN, USA), rabbit anti-Nav1.8 (1:200, ASC-016, Alomone, Jerusalem, Israel), rabbit

(4) Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survivalInternational journal of oncologyJuly 1, 2021Chauvin M, Garambois V, Choblet S, Colombo PE, Chentouf M, Gros L, De Brauwere DP, Duonor-Cerutti M, Dumas K, Robert B, et al.(1:200; irrelevant antibodies used as negative controls), the anti-AMHRII 12G4, and anti-ALK2 (cat. no. AF637), anti-ALK3 (cat. no. AF346) and anti-ALK6 (cat. no. MAB5051) (all from R&D Systems, Inc.) primary antibodies

(5) Circulating activin A during equine gestation and immunolocalization of its receptors system in utero-placental tissues and fetal gonadsJournal of equine scienceJune 1, 2021Dhakal P, Tsunoda N, Nambo Y, Taniyama H, Nagaoka K, Watanabe G, Taya K.coated with 3-aminopropyltriethoxysilane. Goat polyclonal antibodies against activin receptors IA (AF637) and IIB (AF339) were purchased from R&D Systems (Minneapolis, MN, U.S.A.). Goat polyclonal antibody

(6) Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewalCell death & diseaseSeptember 11, 2018Toofan P, Busch C, Morrison H, O'Brien S, Jørgensen H, Copland M, Wheadon H.

(7) Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polypsScientific reportsJanuary 24, 2018Tengroth L, Arebro J, Larsson O, Bachert C, Georén SK, Cardell LO.

(8) The combined mechanism of bone morphogenetic protein- and calcium phosphate-induced skeletal tissue formation by human periosteum derived cellsEuropean cells & materialsJanuary 5, 2016Bolander J, Ji W, Geris L, Bloemen V, Chai YC, Schrooten J, Luyten FP.antibody incubation. Next, cells were incubated overnight at 4 °C with human specific antibody ALK2 (AF637, R&D Systems), ALK3 (NBP2-37421, Novus Biologicals, Abingdon, UK), ALK6 (Mab5051, R&D Systems, Abington,

(9) Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2Biochemical and biophysical research communicationsDecember 12, 2014Fujimoto M, Ohte S, Shin M, Yoneyama K, Osawa K, Miyamoto A, Tsukamoto S, Mizuta T, Kokabu S, Machiya A, et al.

(10) Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid IThe Journal of neuroscience : the official journal of the Society for NeuroscienceDecember 12, 2007Zhu W, Xu P, Cuascut FX, Hall AK, Oxford GS.goat polyclonal antibodies to activin receptors were also purchased from R&D Systems (RIA catalog #AF637; RIB catalog # AF222; RIIB catalog #AF339; RIIA catalog #AF340). PKC␧ polyclonal antibody was purchased

(11) EphB4 provides survival advantage to squamous cell carcinoma of the head and neckInternational journal of cancerSeptember 15, 2006Masood R, Kumar SR, Sinha UK, Crowe DL, Krasnoperov V, Reddy RK, Zozulya S, Singh J, Xia G, Broek D, et al.

(12) Differential effects of activin A on basal and gonadotrophin-induced secretion of inhibin A and progesterone by granulosa cells from preovulatory (F1-F3) chicken folliclesReproductionNovember 1, 2002TM Lovell, RT Gladwell, NP Groome, PG Knightthe extracellular domain of purified recombinant human activin receptor (ActR) IA (Catalogue number AF637), ActRIB (Catalogue number AF222), ActRIIA (Catalogue number AF340) or ActRIIB (Catalogue number AF339).

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Activin RIA/ALK-2 Antibody

Activin RIA/ALK-2 Antibody

Activin RIA/ALK-2 Antibody

Activin RIA/ALK-2 Antibody

Activin RIA/ALK-2 Antibody

Activin RIA/ALK-2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (12)

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Activin RIA/ALK-2 Antibody from R&D Systems, a Bio-Techne Brand

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