Human RANK/TNFRSF11A Antibody AF683 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman RANK/TNFRSF11A Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF683
NCBI Gene AliasesODFR, OFE, TRANCE-R, FEO, CD265, PDB2, RANK, OPTB7, TRANCER, LOH18CR1, OSTS
ApplicationsImmunohistochemistry,Western Blot,Agonist Activity,Immunocytochemistry
TargetRANK/TNFRSF11A
ReactivityHuman
HostGoat
IsotypeIgG
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Quantity100 ug (also 25 ug)
NCBI Full Gene NameTNF receptor superfamily member 11a
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human RANK, Gln29-Gly213, Accession # Q9Y6Q6
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Analysis of RANK-c interaction partners identifies TRAF3 as a critical regulator of breast cancer aggressivenessNeoplasia (New York, N.Y.)November 1, 2022Sirinian C, Papanastasiou AD, Karayel O, Degn SE, Peroukidis S, Chaniotis D, Nonni A, Repanti M, Kriegsmann M, Makatsoris T, et al.employed in this study were: Fibronectin (sc-52331; 1:200, SCBT), Snail (SN9H2, #4719; 1:1000, CST), RANK (af683; 1:400, R&D systems), actin (MAB1501; 1:1000, Millipore, MA), IκB-α (112B2, #9247; 1:1000, CST), p-IκB-α

(2) RANK signaling increases after anti-HER2 therapy contributing to the emergence of resistance in HER2-positive breast cancerBreast cancer research : BCRMarch 30, 2021Sanz-Moreno A, Palomeras S, Pedersen K, Morancho B, Pascual T, Galván P, Benítez S, Gomez-Miragaya J, Ciscar M, Jimenez M, et al.membranes (Millipore). Antibodies against the following proteins were used for probing: RANK (R&D Systems AF683), p-HER2 (#2249), HER2 (#2165), p-EGFR (#3777), EGFR (#4267), p-ERK1/2 (#9101), ERK1/2 (#9102), p-AKT

(3) The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung MetastasesCancersOctober 24, 2018Navet B, Ando K, Vargas-Franco JW, Brion R, Amiaud J, Mori K, Yagita H, Mueller CG, Verrecchia F, Dumars C, et al.sections. Immunohistochemistry was performed with antibodies against RANK (Goat polyclonal antibody AF683 from R&D Systems (Abingdon, UK), dilution 1/20), RANKL (Goat polyclonal antibody AF626 from R&D Systems

(4) Identification of novel human receptor activator of nuclear factor-kB isoforms generated through alternative splicing: implications in breast cancer cell survival and migrationBreast cancer research : BCRJuly 23, 2012Papanastasiou AD, Sirinian C, Kalofonos HP.Biosciences, Uppsala, Sweden). The following primary antibodies were used: anti-human RANK antibodies: (AF683, 1 μg/ml, extracellular domain R&D systems, Abingdon, UK), (sc-9072, 0.2 μg/ml, intracellular domain

(5) IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineageJournal of immunology (Baltimore, Md. : 1950)August 15, 2010Gupta N, Barhanpurkar AP, Tomar GB, Srivastava RK, Kour S, Pote ST, Mishra GC, Wani MR.

(6) Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophilsArthritis Research & TherapyJanuary 1, 2007Patrice E Poubelle, Arpita Chakravarti, Maria J Fernandes, Karine Doiron, Andrée-Anne Marceau(TBS) with 6% Tween 20 for 60 minutes, incubated with 0.2 μg/ml of a goat anti-human RANK IgG Ab (no. AF683; R&D Systems, Inc.), washed three times in TBS-Tween, and incubated with 0.04 μg/ml of a rabbit HRP-conjugated

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RANK/TNFRSF11A Antibody

RANK/TNFRSF11A Antibody

RANK/TNFRSF11A Antibody

Human RANK/TNFRSF11A Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (6)

Reviews

Human RANK/TNFRSF11A Antibody from R&D Systems, a Bio-Techne Brand

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