Mouse VCAM-1/CD106 Antibody AF643 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse VCAM-1/CD106 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberAF643
Quantity100 ug (also 25 ug)
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Simple Western,Neutralization,CyTOF-ready,Cell Selection
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
ConcentrationLYOPH
PurityAntigen Affinity-purified
ReactivityHuman,Mouse,Rat,Transgenic Mouse
HostGoat
TargetVCAM-1/CD106
IsotypeIgG
Antibody TypePrimary Antibodies
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse VCAM-1/CD106, Phe25-Glu698, Accession # P29533
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namevascular cell adhesion molecule 1
NCBI Gene AliasesCD106, Vcam-1

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) PHLDA1 is a shared diagnostic and key mediator of inflammatory fibrosis in heart and kidneyFrontiers in ImmunologyFebruary 5, 2026Lei Hua, Liangru Shen, Yongshou Tao, Chentong Wang, Xiaohang Shao1:100), PHLDA1 (sc-23866, Santa Cruz, dilution: 1:50), p65 (ab16502, Abcam, dilution: 1:300), VCAM1 (AF643, R&D Systems, dilution: 1: 400). Nikon A1R confocal microscope was used subsequently for taking images. 2.2.13

(2) Multi-cellular phenotypic dynamics during the progression of an immunocompetent breast cancer modeliScienceNovember 21, 2025Gsell L, Watson SS, Sutevski I, Massara M, Soukup K, Eroglu A, Mold JE, Cougnoux A, Joyce JA, Hausser J.anti-LY6C (+LY6G),ThermoFisher Scientific,Cat #14-5931-82 Polyclonal Goat anti-VCAM1,Bio-Techne,Cat #AF643 Polyclonal anti-Crabp1,Proteintech,Cat #12588-1-AP Polyclonal Rabbit anti-Laminin,Novus Biologicals,Cat

(3) RIPK3 Protects Against Endothelial Activation and Vascular Permeability in a Mouse Model of Ischemia-Reperfusion InjuryArterioscler Thromb Vasc BiolOctober 30, 2025Charmain F. Johnson, Christopher M. Schafer, Kathryn Y. Burge, Brian G. Coon, Hala Chaaban, Courtney T. Griffin(1:50, R&D Systems; AF114), goat-anti-VCAM-1 (vascular cell adhesion molecule-1; 1:100, R&D Systems; AF643), rabbit-anti-NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells; p65; 1:700, Cell Signaling

(4) RIPK3 Protects Against Endothelial Activation and Vascular Permeability in a Mouse Model of Ischemia-Reperfusion InjuryArteriosclerosis, Thrombosis, and Vascular BiologyOctober 30, 2025Charmain F. Johnson, Christopher M. Schafer, Kathryn Y. Burge, Brian G. Coon, Hala Chaaban, Courtney T. Griffin(1:50, R&D Systems; AF114), goat-anti-VCAM-1 (vascular cell adhesion molecule-1; 1:100, R&D Systems; AF643), rabbit-anti-NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells; p65; 1:700, Cell Signaling

(5) The Influence of VEGFR-2 Blockade and Focused Ultrasound (FUS) Blood-Brain Barrier Opening on the Glioma-Immune LandscapeNeuro-Oncology AdvancesOctober 17, 2025Katherine M Nowak, Matthew R Hoch, Victoria R Breza, Catherine M Gorick, Ji Song, Anna C Debski, Joshua D Samuels, Matthew R DeWitt, Benjamin W Purow, Timothy N Bullock, et al.anti-ICAM (1:500, ThermoFisher #10020-1-AP), and goat antimouse VCAM-1/CD106 (1:1000, R&D Systems #AF643). After washing the slides 3x for 10 min in 0.1% Tween-20 PBS, sections were incubated for 1 hr at room

(6) Interleukin-1 regulates myeloid cell trafficking and cerebral blood flow following intracerebral haemorrhageDisease Models & MechanismsOctober 1, 2025Jack Barrington, Jack Rivers-Auty, Patrick Strangward, Sabrina Tamburrano, Nikolett Lénárt, Tessa Swanton, Eloise Lemarchand, Adrian R. Parry-Jones, Ádám Dénes, David Brough, et al.(5 µg ml−1, ab19808, Abcam, RRID:AB_445160), goat-anti-vascular cell adhesion protein 1 (2 µg ml−1, AF643, R&D Systems, RRID:AB_355499), goat-anti-cyclooxygenase-2 (0.5 µg ml−1, AF4198, R&D Systems, RRID:AB_2229909)

(7) Rbpj deletion in hepatic progenitor cells attenuates endothelial responses and fibrosis in DDC-fed miceHepatol CommunJuly 1, 2025Sanghoon Lee, Lu Ren, Weiwei Li, Aditi Paranjpe, Ping Zhou, Andrew Potter, Stacey S. Huppert, Soona Shin(Abcam ab81289), αSMA (Abcam ab7817), GFAP (Thermo Fisher Scientific 14-9892-82), and VCAM1 (R&D Systems AF643). TSA Plus Cyanine 3 System (PerkinElmer NEL744001KT) was used to amplify signals generated using antibodies

(8) Rbpj deletion in hepatic progenitor cells attenuates endothelial responses and fibrosis in DDC-fed miceHepatol CommunJune 19, 2025Sanghoon Lee, Lu Ren, Weiwei Li, Aditi Paranjpe, Ping Zhou, Andrew Potter, Stacey S. Huppert, Soona Shin(Abcam ab81289), αSMA (Abcam ab7817), GFAP (Thermo Fisher Scientific 14-9892-82), and VCAM1 (R&D Systems AF643). TSA Plus Cyanine 3 System (PerkinElmer NEL744001KT) was used to amplify signals generated using antibodies

(9) Steatohepatitis-induced vascular niche alterations promote melanoma metastasisCancer MetabJanuary 28, 2025Johannes Hoffmann, Julia Schüler, Bianca Dietsch, Sina Wietje Kürschner-Zacharias, Carsten Sticht, Felix A. Trogisch, Maren Schreitmüller, Tinja Baljkas, Kai Schledzewski, Manuel Reinhart, et al.AB_891527), rabbit anti-ICAM1 (10,020–1-AP, Proteintech, USA, RRID: AB_2121773), goat anti-VCAM1/CD106 (AF643, R&D Systems, USA, RRID: AB_355499), rat anti-CLEC4F/CLECSF13 (MAB2784, R&D Systems, USA, RRID: AB_2081338),

(10) Endothelial RIPK3 minimizes organotypic inflammation and vascular permeability in ischemia-reperfusion injurybioRxiv : the preprint server for biologyNovember 26, 2024Johnson CF, Schafer CM, Burge KY, Coon BG, Chaaban H, Griffin CT.

(11) Spatial transcriptomics defines injury specific microenvironments and cellular interactions in kidney regeneration and diseaseNature CommunicationsSeptember 5, 2024Michal Polonsky, Louisa M. S. Gerhardt, Jina Yun, Kari Koppitch, Katsuya Lex Colón, Henry Amrhein, Barbara Wold, Shiwei Zheng, Guo-Cheng Yuan, Matt Thomson, et al.anti-alpha Smooth Muscle Actin (aSMA, 1:2000, Sigma-Aldrich, A5228), goat anti-Vcam1 (1:200, R&D Systems, AF643), rabbit anti-Vcam1 (1:200, Abcam, ab134047), donkey anti-rabbit AlexaFluor 594 (1:500, Molecular probes,

(12) Limiting extracellular matrix expansion in diet-induced obese mice reduces cardiac insulin resistance and prevents myocardial remodellingMolecular metabolismAugust 1, 2024Musale V, Murdoch CE, Banah AK, Hasib A, Hennayake CK, Dong B, Lang CC, Wasserman DH, Kang L.(Ser465/467)/Smad3 (Ser423/425) (8828, 1:1000, Cell signalling), Smad2/3 (3102, 1:1000, Cell signalling), VCAM-1 (AF643, 1:1000, R&D Systems), BNP (ab19645, 1:1000, Abcam), Phospho-p38 MAPK (Thr180/Tyr182) (9211, 1:1000,

(13) Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolutionbioRxiv : the preprint server for biologyMay 31, 2024Muto Y, Yoshimura Y, Wu H, Chang-Panesso M, Ledru N, Woodward OM, Outeda P, Cheng T, Mahjoub MR, Watnick TJ, et al.

(14) Kupffer Cell Inactivation Alters Endothelial Cell Adhesion Molecules in Cecal Ligation and Puncture-Induced SepsisBiomoleculesJanuary 9, 2024Manandhar S, Gaddam RR, Chambers S, Bhatia M.Minneapolis, MN, USA/AF796",1:1000 VCAM-1,Primary/Goat polyclonal,"R&D System, Minneapolis, MN, USA/AF643",1:200 LYVE-1,Primary/Rabbit polyclonal,"Abcam, Cambridge, UK/ab14917",1:100 CD31,Primary/Rabbit polyclonal,"Abcam,

(15) Spleen Tyrosine Kinase phosphorylates VE-cadherin to cause endothelial barrier disruption in acute lung injuryThe Journal of biological chemistryDecember 1, 2023Shadab M, Slavin SA, Mahamed Z, Millar MW, Najar RA, Leonard A, Pietropaoli A, Dean DA, Fazal F, Rahman A.Phospho-VE-cadherin (Tyr658) (#44-1144G) antibody was from Thermo Fisher. ICAM-1 (#AF796) and VCAM-1 (#AF643) antibodies were purchased from R&D Systems. Phospho-VE-cadherin (Tyr685) (#AB119785) antibody was purchased

(16) Extracellular Matrix Abnormalities Contribute to Cardiac Insulin Resistance and Associated Dysfunction in Diet-induced Obese MicebioRxivNovember 21, 2023Vishal Musale, Colin E. Murdoch, Ayman K. Banah, Annie Hasib, Chandani K. Hennayake, Bo Dong, Chim C. Lang, David H. Wasserman, Li Kang(Ser465/467)/Smad3 (Ser423/425) (8828, 1:1000, Cell signalling), Smad2/3 (3102, 1:1000, Cell signalling), VCAM-1 (AF643, 1:1000, R&D Systems), BNP (ab19645, 1:1000, Abcam), Phospho-p38 MAPK (Thr180/Tyr182) (9211, 1:1000,

(17) Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesisImmunityNovember 14, 2023Mytrang H. Do, Wei Shi, Liangliang Ji, Erik Ladewig, Xian Zhang, Raghvendra M. Srivastava, Kristelle J. Capistrano, Chaucie Edwards, Isha Malik, Briana G. Nixon, et al.F4/80,eBioscience,BM8 Anti-mouse Ki67,eBioscience,SolA15 Anti-mouse Vcam1,eBioscience,429 Anti-mouse Vcam1,R&D Systems,AF643 Anti-mouse Protein C receptor,Thermo Scientific,PA5-47382 DAPI,Thermo Scientific,D1306 ,, Antibodies

(18) Extracellular SOD modulates canonical TNFα signaling and α5β1 integrin transactivation in vascular smooth muscle cellsFree Radical Biology and MedicineNovember 1, 2023Hyehun Choi, Michael R. Miller, Hong-Ngan Nguyen, Victoria E. Surratt, Stephen R. Koch, Ryan J. Stark, Fred S. LambIntegrin β1 (#34971) obtained from Cell Signaling Technology (Danvers, MA), ecSOD (#AF4817) and VCAM (#AF643) from R&D Systems (Minneapolis, MN), PCNA (#05-347, MilliporeSigma, Burlington, MA), iNOS (#610328,

(19) Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial CellsInternational journal of molecular sciencesSeptember 4, 2023Manandhar S, Chambers S, Miller A, Ishii I, Bhatia M.Minneapolis, MN, USA/AF796",1: 1000 VCAM-1,Primary/Goat polyclonal,"R&D System, Minneapolis, MN, USA/AF643",1: 200 LYVE-1,Primary/Rabbit polyclonal,"Abcam, Cambridge, UK/ab14917",1:100 CD31,Primary/Rabbit

(20) Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male miceNature communicationsJuly 25, 2023Yu L, Xu L, Chu H, Peng J, Sacharidou A, Hsieh HH, Weinstock A, Khan S, Ma L, Durán JGB, et al.

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VCAM-1/CD106 Antibody

VCAM-1/CD106 Antibody

VCAM-1/CD106 Antibody

VCAM-1/CD106 Antibody

VCAM-1/CD106 Antibody

Mouse VCAM-1/CD106 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (69)

Reviews

Mouse VCAM-1/CD106 Antibody from R&D Systems, a Bio-Techne Brand

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