Human M-CSF Antibody AF216 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman M-CSF Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF216
NCBI Gene AliasesPG-M-CSF, CSF-1, MCSF
ApplicationsWestern Blot,Neutralization,Immunocytochemistry,Cell Culture
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
TargetM-CSF
ReactivityHuman
HostGoat
IsotypeIgG
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
NCBI Full Gene Namecolony stimulating factor 1
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human M-CSF, Glu33-Ser190, Accession # NP_757350
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) In the diffuse large B-cell lymphoma microenvironment, SIRT1 is upregulated and correlated with a pro-inflammatory macrophage signature and autophagy-related gene expressionFrontiers in ImmunologyFebruary 4, 2026Miguel Resanoa, Peio Azcoaga, Naike Salvador, Alba Delgado, Claudia Rodiño, Matthieu Schoenhals, Mounia S. Brazaincubated TMA sections with anti-CD80 (Novus Biologicals, AF140, USA), anti-M-CSF (Novus Biologicals, AF216, USA), anti-SIRT1 (Abcam, Ab110304, UK) and anti-SIRT3 (Abcam, Ab217319, UK) antibodies at 4 °C overnight,

(2) LARRPM restricts lung adenocarcinoma progression and M2 macrophage polarization through epigenetically regulating LINC00240 and CSF1Cellular & molecular biology lettersOctober 11, 2022Li Y, Chen C, Liu HL, Zhang ZF, Wang CL.profiles and determined to be mycoplasma free. LUAD cells were treated with 0.2 µg/ml anti-CSF1 antibody (AF216; R&D Systems, Minneapolis, MN, USA) and THP-1 cells were treated with 100 ng/ml phorbol-12-myristate-13-acetate

(3) Crosstalk between macrophage-derived PGE(2) and tumor UHRF1 drives hepatocellular carcinoma progressionTheranosticsJanuary 1, 2022Zhang J, Zhang H, Ding X, Hu J, Li Y, Zhang J, Wang H, Qi S, Xie A, Shi J, et al.were cultured in 10-cm dishes for 48 hours. The supernatants were mixed with 2 μg/mL of CSF1 antibody (AF216, R&D Systems, USA), CCL14 antibody (MAB3241, R&D Systems, USA) or isotype IgG for 24 hours. These supernatants

(4) Long non-coding RNA HOMER3-AS1 drives hepatocellular carcinoma progression via modulating the behaviors of both tumor cells and macrophagesCell death & diseaseNovember 23, 2021Pu J, Li W, Wang A, Zhang Y, Qin Z, Xu Z, Wang J, Lu Y, Tang Q, Wei H.indicated, cells were treated with 10 μM ICG-001 (Selleck, Houston, TX, USA), 0.2 µg/mL Anti-CSF-1 (AF216, R&D Systems, Minneapolis, MN, USA), or 100 ng/ml phorbol-12-myristate-13-acetate (PMA, Sigma Aldrich,

(5) Autocrine signaling by receptor tyrosine kinases in urothelial carcinoma of the bladderPloS oneJanuary 1, 2021Lee YH, Lee MM, De Silva DM, Roy A, Wright CE, Wong TK, Costello R, Olaku O, Grubb RL 3rd, Agarwal PK, et al.Massachusetts USA). Antibodies against Met (cat. # BAF358, AF276), RYK (cat. #AF4907), CSF1 (cat. #AF216), CSF1R (cat. #MAB3291) and GAS6 (cat. # AF885) were obtained from R&D Systems (Minneapolis, Minnesota

(6) Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growthRedox biologyApril 1, 2019Zhang J, Li H, Wu Q, Chen Y, Deng Y, Yang Z, Zhang L, Liu B.neutralizing antibody (#MAB282), IL8 neutralizing antibody (#MAB208) and CSF-1 neutralizing antibody (#AF216) were R&D Systems. Cell culture reagents were obtained from Invitrogen. All other reagents were from

(7) Fucoidan modulates cytokine production and migration of THP‑1‑derived macrophages via colony‑stimulating factor‑1Molecular medicine reportsApril 1, 2017Li P, Wang H, Shao Q, Kong B, Qu X.(Merck Millipore, Darmstadt, Germany). Monoclonal anti‑human M‑CSF neutralizing antibodies (NAb; cat. no. AF216; 100 ng/ml) were obtained from R&D Systems, Inc. Preparation of fucoidan. Fucoidan puriﬁed from F. vesicu‑ losus

(8) Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesisBloodFebruary 26, 2009Chen H, Campbell RA, Chang Y, Li M, Wang CS, Li J, Sanchez E, Share M, Steinberg J, Berenson A, et al.

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M-CSF Antibody

M-CSF Antibody

Human M-CSF Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Human M-CSF Antibody from R&D Systems, a Bio-Techne Brand

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