Mouse IL-1 RII Antibody AF563 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse IL-1 RII Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF563
NCBI Gene AliasesIl1r-2, CD121b
ApplicationsELISA Development,Flow Cytometry,Immunohistochemistry,Western Blot,CyTOF-ready
Quantity100 ug (also 25 ug)
TargetIL-1 RII
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
ReactivityMouse,Primate - Chlorocebus aethiops (African Green Monkey)
HostGoat
NCBI Full Gene Nameinterleukin 1 receptor, type II
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-1 RII, Phe14-Glu355 (predicted), Accession # P27931
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Critical Role of IL1R2-ENO1 Interaction in Inhibiting Glycolysis-Mediated Pyroptosis for Protection Against Lethal SepsisAdvanced science (Weinheim, Baden-Wurttemberg, Germany)October 1, 2025Tan C, Ma H, Chen J, Ma G, Jha A, Tan S, Zhu Y, Liu M, Liu K, Xiao X, et al.antibody against enolase‐1 (dilution 1:200; Cat. Ab227978, Abcam,) and IL1R2 (dilution 1:200; Cat. No. AF563, R&D systems) overnight at 4 °C. Goat anti‐rabbit IgG (dilution 1:250; Cat. No. A21244, Invitrogen)

(2) A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contractionImmunityJune 10, 2025Jubayer Rahman, Jack A. Bibby, Parul Singh, Nicolas S. Merle, Erin E. West, Andrea Bohrer, Katrin Mayer-Barber, Chengyu Liu, Lauren R. Brinster, Behdad Afzali, et al.AB_493312 PE-anti-mouse IL-17A (TC11-18H10.1),Biolegend,Cat# 506904; RRID: AB_315464 Anti-mouse IL-1R2 (AF563),R & D Systems,Cat# AF563; RRID: AB_2125055 Brilliant Violet 711-anti-mouse/human Ki67 (B56),BD Biosciences,Cat#

(3) BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1Science advancesJune 17, 2022Singh N, Benoit MR, Zhou J, Das B, Davila-Velderrain J, Kellis M, Tsai LH, Hu X, Yan R.6E10",803003,AB_2564652,BioLegend TREM2,ab86491,AB_1925525,Abcam TLR4,sc-293072,AB_10611320,Santa Cruz BACE1 (D10E5),5606,AB_1903900,Cell Signaling Inc. Iba1,019-19741,AB_839504,Wako IL-1 RII,AF563,AB_2125055,R and D Systems Rac-1,ARC03,AB_2721173,Cytoskeleton Inc. p38-P-MAPK(Thr180/Tyr182)(D3F9),4511,AB_2139682,Cell Signaling

(4) Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory ResponsesJournal of immunology (Baltimore, Md. : 1950)April 1, 2017Martin P, Palmer G, Rodriguez E, Seemayer CA, Palomo J, Talabot-Ayer D, Gabay C.

(5) ADAM17 regulates IL-1 signaling by selectively releasing IL-1 receptor type 2 from the cell surfaceCytokineFebruary 1, 2015Uchikawa S, Yoda M, Tohmonda T, Kanaji A, Matsumoto M, Toyama Y, Horiuchi K.

(6) Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3Journal of immunology (Baltimore, Md. : 1950)June 1, 2007O'Connor JC, Sherry CL, Guest CB, Freund GG.

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IL-1 RII Antibody

IL-1 RII Antibody

IL-1 RII Antibody

IL-1 RII Antibody

Mouse IL-1 RII Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Mouse IL-1 RII Antibody from R&D Systems, a Bio-Techne Brand

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