IL-2 Antibody AF-202-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF-202-NA
NCBI Gene Aliaseslymphokine, TCGF, IL-2
ApplicationsELISA,Western Blot,Neutralization,Immunocytochemistry,ELISA Capture,ELISA Detection
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
IsotypeIgG
HostGoat
TargetIL-2
NCBI Full Gene Nameinterleukin 2
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human IL-2, Ala21-Thr153, Accession # P60568
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human IL-2 in direct ELISAs and Western blots. In direct ELISAs, greater than 50% cross-reactivity with recombinant rabbit IL-2 is observed and less than 20% cross-reactivity with recombinant bovine IL-2, recombinant mouse IL-2 and recombinant rat IL-2 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity☆Computational and Structural Biotechnology JournalMarch 4, 2025Amy Dashwood, Ntombizodwa Makuyana, Rob van der Kant, Arman Ghodsinia, Alvaro R. Hernandez, Stephanie Lienart, Oliver Burton, James Dooley, Magda Ali, Lubna Kouser, et al.with anti-IL2 antibodies ((mouse: clone JES6–1A12, BioLegend, 503701) (human: polyclonal, Bio-Techne, AF-202-NA)). The detection antibody was HRP-conjugated anti-Histag (BioLegend, 652503). Standard curves were created

(2) Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8(+) T cellsNature immunologyMay 1, 2023Corria-Osorio J, Carmona SJ, Stefanidis E, Andreatta M, Ortiz-Miranda Y, Muller T, Rota IA, Crespo I, Seijo B, Castro W, et al.

(3) Discovery of a Conditionally Activated IL-2 that Promotes Antitumor Immunity and Induces Tumor RegressionCancer immunology researchMay 3, 2022Nirschl CJ, Brodkin HR, Hicklin DJ, Ismail N, Morris K, Seidel-Dugan C, Steiner P, Steuert Z, Sullivan JM, Tyagi E, et al.according to the manufacturer's protocol. The primary anti-human IL-2 was purchased from R&D Systems (AF-202-NA) and the anti-goat secondary was purchased from Jackson Labs (AB_2338513). Samples and antibodies were

(4) Airplug-mediated isolation and centralization of single T cells in rectangular microwells for biosensingAdvanced therapeuticsJanuary 1, 2020Sukumar P, Deliorman M, Brimmo AT, Alnemari R, Elsori D, Chen W, Qasaimeh MA.was allowed for 60, 120, and 240 minutes of incubation. Afterward, secondary anti-IL-2 antibodies (AF-202-NA, R&D Systems; conjugated to red Alexa Fluor 594 dyes and used at 20 μg/mL concentration) were used to

(5) Multiplexed Elispot assayJournal of immunological methodsFebruary 28, 2009Harriman WD, Collarini EJ, Cromer RG, Dutta A, Strandh M, Zhang F, Kauvar LM.with 1% of BSA. Multiplexed assay conditions Capture antibodies R&D Systems: IFNγ (MAB2852), IL2 (AF202NA), IL4 (AF204NA), IL5 (MAB405), IL6(AF206NA); Pierce: IL10 (M010) Detection antibodies R&D Systems:

(6) Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10Journal of immunology (Baltimore, Md. : 1950)May 1, 2004Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA.

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IL-2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-2 Antibody from R&D Systems, a Bio-Techne Brand

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