Common gamma Chain/IL-2 R gamma Antibody AF284 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCommon gamma Chain/IL-2 R gamma Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberAF284
NCBI Gene AliasesIMD4, CD132, IL-2RG, SCIDX, CIDX, SCIDX1, P64
ApplicationsFlow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Neutralization,CyTOF-ready
Quantity250 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
TargetCommon gamma Chain/IL-2 R gamma
ReactivityHuman
Conjugate/TagUnconjugated
IsotypeIgG
NCBI Full Gene Nameinterleukin 2 receptor subunit gamma
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human Common gamma Chain/IL-2 R gamma, Leu23-Asn254, Accession # P31785
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human Common gamma Chain/IL-2 R gamma in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse IL-2 R gamma is observed, less than 10% cross-reactivity with recombinant human (rh) IL-2 Rß is observed, and less than 2% cross-reactivity with rhIL-2 R alpha is observed.

Sizes Available: 250 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Loss of Interleukin-13-Receptor-Alpha-1 Induces Apoptosis and Promotes EMT in Pancreatic CancerInternational journal of molecular sciencesMarch 26, 2022Shi J, Shen X, Kang Q, Yang X, Denzinger M, Kornmann M, Traub B.anti-p-Akt1/2/3(sc-7985-R, 1:200) from Santa Cruz Biotechnology (Dallas, Texas, USA), goat anti-human common γ chain (AF284, 0.1 μg/mL, R&D Systems, Minneapolis, MN, USA), rabbit anti-STAT3 antibody (#4904, 1:2000), anti-phospho-STAT3

(2) Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic ImmunityFrontiers in immunologyJanuary 1, 2020Rueschenbaum S, Cai C, Schmidt M, Schwarzkopf K, Dittmer U, Zeuzem S, Welsch C, Lange CM.Abcam, Sigma, Santa Cruz, and BD Bioscience, respectively. Antibodies against CD127 (MAB306) and CD132 (AF284) were from R&D Systems. Antibodies against phospho-Stat5 (Tyr694, 4322), Stat5 (9363) phospho-GSK3 (Ser21/9,

(3) Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines and matrix-degrading enzymes in vitroPloS oneJanuary 1, 2014Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borzì RM, Meliconi R.IL-13Rα1 chain (Goat AF152 R&D Systems) at a concentration of 1 µg/ml and to a common gamma chain (Goat AF284 R&D Systems) at a concentration of 1 µg/ml. Signals were developed with a biotin/streptavidin amplified,

(4) Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte responseThe Journal of biological chemistryMay 14, 2010Rose T, Pillet AH, Lavergne V, Tamarit B, Lenormand P, Rousselle JC, Namane A, Thèze J.

(5) Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patientsJournal of immunology (Baltimore, Md. : 1950)June 15, 2009Rose T, Lambotte O, Pallier C, Delfraissy JF, Colle JH.

(6) Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patientsJournal of immunology (Baltimore, Md. : 1950)June 1, 2008Zheng CF, Jones GJ, Shi M, Wiseman JC, Marr KJ, Berenger BM, Huston SM, Gill MJ, Krensky AM, Kubes P, et al.

(7) OX40 Ligation of CD4⁺T Cells Enhances Virus-Specific CD8⁺T Cell Memory Responses Independently of IL-2 and CD4⁺T Regulatory Cell InhibitionThe Journal of ImmunologyFebruary 15, 2006Qigui Yu, Feng Yun Yue, Xiao X. Gu, Herbert Schwartz, Colin M. Kovacs, Mario A. OstrowskiCTL responses against two persistent viral infections, EBV and HIV-1. human common ␥-chain (IL-2 R␥ (AF284)), and monoclonal anti-human common ␥-chain (IL-2 R␥ (MAB284)) Abs were purchased from R&D Systems.

(8) Cortactin and dynamin are required for the clathrin-independent endocytosis of gammac cytokine receptorThe Journal of cell biologyJanuary 3, 2005Sauvonnet N, Dujeancourt A, Dautry-Varsat A.third was loaded on SDS-PAGE and analyzed by Western blot with either goat anti-γc receptor (1:1,000, AF284; R&D Systems), mouse anti-rab5 (1:1,000; BD Biosciences), or mouse anti-flotillin 2 (1:2,000; BD Biosciences). Transfection

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Common gamma Chain/IL-2 R gamma Antibody

Common gamma Chain/IL-2 R gamma Antibody

Common gamma Chain/IL-2 R gamma Antibody

Common gamma Chain/IL-2 R gamma Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (8)

Reviews

Common gamma Chain/IL-2 R gamma Antibody from R&D Systems, a Bio-Techne Brand

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