Mouse IL-1ß/IL-1F2 Antibody AB-401-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse IL-1ß/IL-1F2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberAB-401-NA
NCBI Gene AliasesIL-1beta, Il-1b
ApplicationsImmunohistochemistry,Western Blot,Simple Western,Neutralization
TargetIL-1 beta/IL-1F2
HostGoat
Quantity1 mg
ReactivityHuman,Mouse,Rat
Conjugate/TagUnconjugated
IsotypeIgG
NCBI Full Gene Nameinterleukin 1 beta
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
ImmunogenE. coli-derived recombinant mouse IL-1ß/IL-1F2, Val118-Ser269, Accession # P10749
ConcentrationLYOPH
PurityProtein A or G purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Type A cholesterol-dependent cytolysins translocate to the trans-Golgi network for NLRP3 inflammasome activationNature immunologyOctober 1, 2025Xiao N, Kogishi A, Radochonski L, Lei Y, Chen J.(HPA012723), α-tubulin (T9026), and Flag M2 (F1804) were from Sigma-Aldrich. Antibody against IL-1β (AB-401-NA) was from R&D Systems. Antibodies against GOLGA4 (611280), GGA3 (612310), GM130 (610822), and EEA1 (610456)

(2) Exploring Candesartan, an angiotensin II receptor antagonist, as a novel inhibitor of NLRP3 inflammasome: alleviating inflammation in Neisseria gonorrhoeae infectionBMC infectious diseasesNovember 22, 2024Lin WY, Tsui JL, Chiu HW, Wong WT, Wu CH, Hsu HT, Ho CL, Yeh SP, Rao YK, Chen A, et al.gonorrhoeae-infected macrophages. Materials and methods Chemicals and reagents IL-1β antibody (AB-401-NA) was procured from R&D Systems (Minneapolis, MN). We sourced antibodies against NLRP3 (AG-20B-0014)

(3) Euphorbia factor L2 alleviated gouty inflammation by specifically suppressing both the priming and activation of NLRP3 inflammasomeInternational immunopharmacologySeptember 10, 2024Li Y, Zhuang Y, Chen Y, Wang G, Tang Z, Zhong Y, Zhang Y, Wu L, Ji X, Zhang Q, et al.

(4) Thymol improves ischemic brain injury by inhibiting microglia-mediated neuroinflammationBrain research bulletinSeptember 1, 2024Zhao C, Sun L, Zhang Y, Shu X, Hu Y, Chen D, Zhang Z, Xia S, Yang H, Bao X, et al.

(5) Cinnamaldehyde inhibits the NLRP3 inflammasome by preserving mitochondrial integrity and augmenting autophagy in Shigella sonnei-infected macrophagesJournal of InflammationJune 5, 2024Kuo-Feng Hua, Yu-Bei Lin, Hsiao-Wen Chiu, Wei-Ting Wong, Shuk-Man Ka, Chun-Hsien Wu, Wen-Yu Lin, Chien-Chun Wang, Chung-Hua Hsu, Hsien-Ta Hsu, et al.(AG-20B-0044) were purchased from Adipogen International (San Diego, CA). Antibodies against IL-1β (AB-401-NA) were purchased from R&D Systems (Minneapolis, MN). Mouse LC3 CRISPR/Cas9 knockout plasmids (sc-426,563

(6) Honokiol Exhibits Anti-NLRP3 Inflammasome and Antimicrobial Properties in Neisseria gonorrhoeae-Infected MacrophagesJournal of Inflammation ResearchMay 29, 2024Kuo-Feng Hua, Hsien-Ta Hsu, May-Shu Huang, Hsiao-Wen Chiu, Wei-Ting Wong, Chien-Hsiu Peng, Yu-Bei Lin, Ann Chen, Chien-Chun Wang, Chung-Hua Hsu, et al.NLRP3 (AG-20B-0014) were sourced from Adipogen International (San Diego, CA). Antibodies against IL-1β (AB-401-NA) were obtained from R&D Systems (Minneapolis, MN). Antibodies against caspase-11, p-MAPK (#9910), p-IKKα/β

(7) Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic strokeCell reports. MedicineMay 21, 2024Guan X, Zhu S, Song J, Liu K, Liu M, Xie L, Wang Y, Wu J, Xu X, Pang T.AB_2783550 Rabbit anti-GSDMD,Abcam,Cat# ab219800; RRID: AB_2888940 Goat anti-IL-1β,R&D Systems,Cat# AB-401-NA; RRID: AB_354347 Rabbit anti-IBA1,Wako,Cat# 01919741; RRID: AB_839504 Goat anti-IBA1,NOVUS,Cat# NB100-1028;

(8) "TRAF6-TAK1-IKKβ pathway mediates TLR2 agonists activating ""one-step"" NLRP3 inflammasome in human monocytes"CytokineSeptember 1, 2023Chen M, Yu S, Gao Y, Li J, Wang X, Wei B, Meng G.

(9) N(6)-Methyladenosine and Reader Protein YTHDF2 Enhance the Innate Immune Response by Mediating DUSP1 mRNA Degradation and Activating Mitogen-Activated Protein Kinases during Bacterial and Viral InfectionsmBioFebruary 28, 2023Feng J, Meng W, Chen L, Zhang X, Markazi A, Yuan W, Huang Y, Gao SJ.p-JNK (catalog number 4668S; CST), DUSP1 (catalog number NBP2-67909; Novus), IL-1β (catalog number AB-401-NA; R&D Systems), or ALKBH5 (catalog number HPA007196; Sigma) overnight at 4°C. The membrane was washed

(10) GSK3β mediates the spatiotemporal dynamics of NLRP3 inflammasome activationCell death and differentiationOctober 1, 2022Arumugam S, Qin Y, Liang Z, Han SN, Boodapati SLT, Li J, Lu Q, Flavell RA, Mehal WZ, Ouyang X.

(11) Repositioning of the Angiotensin II Receptor Antagonist Candesartan as an Anti-Inflammatory Agent With NLRP3 Inflammasome Inhibitory ActivityFrontiers in immunologyJanuary 1, 2022Lin WY, Li LH, Hsiao YY, Wong WT, Chiu HW, Hsu HT, Peng YJ, Ho CL, Chernikov OV, Cheng SM, et al.Histopaque-1077 (10771-100ML) were purchased from Sigma–Aldrich (St. Louis, MO). Antibodies against IL-1β (AB-401-NA) were purchased from R&D Systems (Minneapolis, MN). Antibodies against phospho-MAPK (#9910) were purchased

(12) Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophagesNature communicationsNovember 18, 2021Ding X, Kambara H, Guo R, Kanneganti A, Acosta-Zaldívar M, Li J, Liu F, Bei T, Qi W, Xie X, et al.mouse anti-GSDMD antibody (ab209845, 1:500; Abcam, Cambridge, UK), mouse anti-IL-1-β/IL-1F2 antibody (AB-401-NA, 1:1000; R&D Systems, Minneapolis, MI), antitotal IL-1β antibody (D3H1Z) (#12507, 1:1000; Cell Signaling Technology

(13) Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin CompoundsEnvironmental health perspectivesApril 1, 2021Childers GM, Perry CA, Blachut B, Martin N, Bortner CD, Sieber S, Li JL, Fessler MB, Harry GJ.activated 0:2-lm nitrocellulose membranes (BioRad), then incubated with polyclonal goat antimouse IL-1b (AB-401-NA; R&D Systems; RRI: AB_354347;1:2,500; 1 lg=mL) in 5% low-fat milk at 4°C, overnight. Rinsed membranes

(14) The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion modelScientific reportsOctober 14, 2020Sato K, Tobo A, Mogi C, Tobo M, Yamane N, Tosaka M, Tomura H, Im DS, Okajima F.(DuoSet), Mouse IL-1β ELISA kit (DuoSet), anti-mouse TNF-α antibody (AB-410-NA), anti-mouse IL-1β (AB-401-NA) antibody, and anti-mouse vascular cell adhesion molecule-1 (VCAM-1, AF643) antibody were from R&D Systems

(15) Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to Listeria monocytogenesJournal of immunology (Baltimore, Md. : 1950)August 1, 2020Jeong YH, Walsh MC, Yu J, Shen H, Wherry EJ, Choi Y.forms of caspase-1 and IL-1β were detected using anti-caspase-1 (Adipogen), anti-IL-1β (R&D Systems; AB-401-NA), with anti-β-actin (Sigma) used for loading control. Statistical Analysis Statistical analyses were

(16) Chemo-Protective Potential of Cerium Oxide Nanoparticles against Fipronil-Induced Oxidative Stress, Apoptosis, Inflammation and Reproductive Dysfunction in Male White Albino RatsMolecules (Basel, Switzerland)July 31, 2020Saleh H, Nassar AMK, Noreldin AE, Samak D, Elshony N, Wasef L, Elewa YHA, Hassan SMA, Saati AA, Hetta HF, et al.Merck Millipore, Burlington, MA, USA) 1:1000 10 mM citrate buffer (pH 6.0) 105 ◦ C, 20 min Goat polyclonal anti-IL1β (AB-401-NA, R&D Systems, Minneapolis, MN, USA) 1:200 10 mM citrate buffer (pH 6.0) 105 ◦ C, 20 min Goat polyclonal anti-PCNA (sc-9857,

(17) A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy InductionFrontiers in immunologyJanuary 1, 2020Wu CH, Gan CH, Li LH, Chang JC, Chen ST, Menon MP, Cheng SM, Yang SP, Ho CL, Chernikov OV, et al.Diego, CA). ASC-GFP plasmids were purchased from Genomics (Taipei, Taiean). Antibody against IL-1β (AB-401-NA) was purchased from R&D systems (Minneapolis, MN). Antibodies against caspase-1 (AG-20B-0044) and NLRP3

(18) Critical Role for the NLRP3 Inflammasome in Mediating IL-1β Production in Shigella sonnei-Infected MacrophagesFrontiers in immunologyJanuary 1, 2020Li LH, Chen TL, Chiu HW, Hsu CH, Wang CC, Tai TT, Ju TC, Chen FH, Chernikov OV, Tsai WC, et al.monoclonal antibody) were purchased from Adipogen International (San Diego, CA). Antibodies against IL-1β (AB-401-NA, polyclonal antibody) were purchased from R&D Systems (Minneapolis, MN). MCC950 was purchased from TargetMol

(19) Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasomeScientific reportsApril 3, 2019Chiu HW, Li LH, Hsieh CY, Rao YK, Chen FH, Chen A, Ka SM, Hua KF.(ab32036) and PKR (ab184257) were purchased from Abcam (Cambridge, UK). The antibody against IL-1β (AB-401-NA) was purchased from R&D systems (Minneapolis, MN). ELISA kits were purchased from Affymetrix eBioscience

(20) Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscleFEBS open bioFebruary 1, 2019Nakazawa H, Ikeda K, Shinozaki S, Yasuhara S, Yu YM, Martyn JAJ, Tompkins RG, Yorozu T, Inoue S, Kaneki M.

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IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

Mouse IL-1ß/IL-1F2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (34)

Reviews

Mouse IL-1ß/IL-1F2 Antibody from R&D Systems, a Bio-Techne Brand

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