IL-12 Antibody AB-219-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-12 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAB-219-NA
NCBI Gene AliasesCLMF, IL-12A, NFSK, NKSF, NKSF2, NKSF1, CLMF2, P35, IMD29, IMD28, IL-12B
ApplicationsBioassay,Western Blot,Neutralization,Cell Culture
ReactivityHuman
Quantity1 mg
HostGoat
Conjugate/TagUnconjugated
IsotypeIgG
TargetIL-12
NCBI Full Gene Nameinterleukin 12B, interleukin 12A
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12 heterodimer, Arg23-Ser219 of p35; Ile23-Ser328 of p40, Accession # P29459 (p35) & P29460 (p40)
ConcentrationLYOPH
PurityProtein A or G purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human IL-12 in direct ELISAs and Western blots. In these formats, less than 2% cross-reactivity with recombinant mouse IL-12 is observed.

Sizes Available: 1 mg

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) mWTX-330, an IL-12 INDUKINE Molecule, Activates and Reshapes Tumor-Infiltrating CD8+ T and NK Cells to Generate Antitumor ImmunityCancer immunology researchJuly 5, 2023Nirschl CJ, Brodkin HR, Domonkos C, Dwyer CJ, Hicklin DJ, Ismail N, Seidel-Dugan C, Steiner P, Steuert Z, Sullivan JM, et al.(intact and protease cleaved) were also analyzed. Samples, primary antibody (anti–IL-12; R&D Systems, AB-219-NA), and secondary antibody (Jackson Labs, 805–035–180) were loaded into a 12–230 kDA Jess separation module

(2) Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylationPLoS pathogensMarch 1, 2020Kong W, Biswas A, Zhou D, Fiches G, Fujinaga K, Santoso N, Zhu J.CD3 (Cat. # 16-0037-85) and CD28 (Cat. # 16-0289-85) were purchased from eBioscience. IL-12 (Cat. # AB-219-NA) and IL-4 (Cat. # AB-204-NA) antibodies were purchased from R&D System. An anti-m5C antibody (Cat. #

(3) A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb AssociationFrontiers in microbiologyJanuary 1, 2017Huang H, Liu S, Jean M, Simpson S, Huang H, Merkley M, Hayashi T, Kong W, Rodríguez-Sánchez I, Zhang X, et al.CD3 (16-0037-85) and CD28 (16-0289-85) were purchased from eBioscience. TGF-β (7754-BH-005), IL-12 (AB-219-NA), and IL-4 (AB-204-NA) antibodies were purchased from R&D System. IL-2 (11011456001) and Nevirapine

(4) A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomesNucleic acids researchDecember 2, 2015Zhong F, Zhou N, Wu K, Guo Y, Tan W, Zhang H, Zhang X, Geng G, Pan T, Luo H, et al.(200-04,PeproTech) and neutralizing antibodies such as anti-IFN-γ (5 μg /ml) (MAB285, R&D) and anti-IL-12 (5μg /ml) (AB-219-NA, R&D Systems). Human primary CD4 T lymphocytes were transfected by using Lipofectamine RNAimax (Life

(5) IL-33 induces IL-9 production in human CD4+ T cells and basophilsPloS oneJanuary 1, 2011Blom L, Poulsen BC, Jensen BM, Hansen A, Poulsen LK.

(6) Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsetsThe Journal of experimental medicineJune 3, 2002Ito T, Amakawa R, Kaisho T, Hemmi H, Tajima K, Uehira K, Ozaki Y, Tomizawa H, Akira S, Fukuhara S.round-bottomed tissue culture plates. In some experiments, neutralizing goat polyclonal anti–human IL-12 Ab (AB-219-NA: 20 μg/ml) (R&D Systems) or a mixture of neutralizing rabbit polyclonal anti–human IFN-α Ab (2,000 neutralization

(7) Generation of Human CD8 T Regulatory Cells by CD40 Ligand–activated Plasmacytoid Dendritic CellsJournal of Experimental MedicineMarch 18, 2002Michel Gilliet, Yong-Jun LiuDickinson). In some experiments, recombinant human IL-12 (2 ng/ml; R&D Systems), neutralizing anti–IL-12 mAb AB-219-NA (10 μg/ml; R&D Systems), or neutralizing anti–IL-10 mAb 12G8 (10 μg/ml; DNAX) were added to the cultures. Proliferation

(8) Differential regulation of human blood dendritic cell subsets by IFNsJournal of immunology (Baltimore, Md. : 1950)March 1, 2001Ito T, Amakawa R, Inaba M, Ikehara S, Inaba K, Fukuhara S.T cells). After 6 days of DC-T cell coculture with or without neutralizing polyclonal Ab to IL-12 (AB-219-NA, 20 ␮g/ml) or IL-10 (AB-217-NA, 20 ␮g/ml; both of goat polyclonal IgG from R&D Systems, Minneapolis,

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IL-12 Antibody

IL-12 Antibody

IL-12 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (8)

Reviews

IL-12 Antibody from R&D Systems, a Bio-Techne Brand

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