4EBP1 Antibody

Product Specs
Item4EBP1 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $459.00Supplier Page View Company Product Page
Catalog NumberNB200-157
Quantity100 ul
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
FormatTris-Citrate/Phosphate (pH 7.0 - 8.0)
PurityImmunogen affinity purified
ReactivityHuman
Target4EBP1
HostRabbit
IsotypeIgG
Antibody TypePrimary Antibodies
ImmunogenThe immunogen recognized by this antibody maps to a region between residue 75 and the C-terminus (residue 118) of human eukaryotic translation initiation factor 4E binding protein 1 using the numbering given in entry NP_004086.1 (GeneID 1978)
ClonalityPolyclonal
Research AreaCancer, Core ESC Like Genes, DNA Repair, DNA replication Transcription Translation and Splicing, Lipid and Metabolism, mTOR Pathway, Stem Cell Markers
NCBI Full Gene Nameeukaryotic translation initiation factor 4E binding protein 1
NCBI Gene AliasesBP-1, PHAS-I, 4EBP1, 4E-BP1
ValidationKnockout Validated
StorageStore at 4C. Do not freeze

Specifications/Features

Available conjugates: Unconjugated

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Site-specific cleavage of the host poly(A) binding protein by the encephalomyocarditis virus 3C proteinase stimulates viral replicationJournal of virologyOctober 1, 2012Kobayashi M, Arias C, Garabedian A, Palmenberg AC, Mohr I.

(2) A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS CellsFrontiers in physiologyJanuary 1, 2012Jozefczuk J, Kashofer K, Ummanni R, Henjes F, Rehman S, Geenen S, Wruck W, Regenbrecht C, Daskalaki A, Wierling C, et al.,Cell Signaling Technology AKT,S473,4058,Cell Signaling Technology PEPCK,,sc-32879,Santa Cruz Biotechnology 4EBP1,,NB200157,Novus Biologicals TSC1,,4906,Cell Signaling Technology TSC2,,3990,Cell Signaling Technology CD36,,AF2519,R&D Systems

(3) Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous micePloS oneJanuary 1, 2012Lang SM, Kazi AA, Hong-Brown L, Lang CH.

(4) Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathwayAmerican journal of physiology. Cell physiologyAugust 1, 2010Winter JN, Fox TE, Kester M, Jefferson LS, Kimball SR.

(5) Hyperoxia inhibits protein synthesis and increases eIF2α phosphorylation in the newborn rat lungAmerican journal of physiology. Lung cellular and molecular physiologyMay 1, 2010Konsavage W, Zhang L, Vary T, Shenberger JS.

(6) Feeding rapidly stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing translation initiationThe Journal of nutritionOctober 1, 2009Wilson FA, Suryawan A, Orellana RA, Kimball SR, Gazzaneo MC, Nguyen HV, Fiorotto ML, Davis TA.

(7) Glucagon acts in a dominant manner to repress insulin-induced mammalian target of rapamycin complex 1 signaling in perfused rat liverAmerican journal of physiology. Endocrinology and metabolismAugust 1, 2009Baum JI, Kimball SR, Jefferson LS.

(8) The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in ratsThe Journal of nutritionJune 1, 2009Norton LE, Layman DK, Bunpo P, Anthony TG, Brana DV, Garlick PJ.

(9) Age-related deficit in load-induced skeletal muscle growthThe journals of gerontology. Series A, Biological sciences and medical sciencesJune 1, 2009Hwee DT, Bodine SC.

(10) Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiationThe Journal of neuroscience : the official journal of the Society for NeuroscienceMay 13, 2009Tyler WA, Gangoli N, Gokina P, Kim HA, Covey M, Levison SW, Wood TL.

(11) Fed levels of amino acids are required for the somatotropin-induced increase in muscle protein synthesisAmerican journal of physiology. Endocrinology and metabolismOctober 1, 2008Wilson FA, Suryawan A, Orellana RA, Nguyen HV, Jeyapalan AS, Gazzaneo MC, Davis TA.

(12) Skeletal and cardiac myopathy in HIV-1 transgenic ratsAmerican journal of physiology. Endocrinology and metabolismOctober 1, 2008Pruznak AM, Hong-Brown L, Lantry R, She P, Frost RA, Vary TC, Lang CH.

(13) Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside prevents leucine-stimulated protein synthesis in rat skeletal muscleThe Journal of nutritionOctober 1, 2008Pruznak AM, Kazi AA, Frost RA, Vary TC, Lang CH.

(14) Stimulation of muscle protein synthesis by somatotropin in pigs is independent of the somatotropin-induced increase in circulating insulinAmerican journal of physiology. Endocrinology and metabolismJuly 1, 2008Wilson FA, Orellana RA, Suryawan A, Nguyen HV, Jeyapalan AS, Frank J, Davis TA.

(15) Eukaryotic translation initiation factor 4F architectural alterations accompany translation initiation factor redistribution in poxvirus-infected cellsMolecular and cellular biologyApril 1, 2008Walsh D, Arias C, Perez C, Halladin D, Escandon M, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Mohr I.

(16) Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesisThe Journal of biological chemistryFebruary 8, 2008Kimball SR, Do AN, Kutzler L, Cavener DR, Jefferson LS.

(17) Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulatedAmerican journal of physiology. Endocrinology and metabolismDecember 1, 2007Suryawan A, Orellana RA, Nguyen HV, Jeyapalan AS, Fleming JR, Davis TA.

(18) Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiationAmerican journal of physiology. Endocrinology and metabolismNovember 1, 2007Orellana RA, Jeyapalan A, Escobar J, Frank JW, Nguyen HV, Suryawan A, Davis TA.

(19) Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent processAmerican journal of physiology. Endocrinology and metabolismAugust 1, 2007Jeyapalan AS, Orellana RA, Suryawan A, O'Connor PM, Nguyen HV, Escobar J, Frank JW, Davis TA.

(20) Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathwayThe Journal of cell biologyJuly 30, 2007Lamouille S, Derynck R.

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4EBP1 Antibody

4EBP1 Antibody

4EBP1 Antibody

4EBP1 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (45)

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4EBP1 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

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