Phospho-PKCtheta (Thr538) Antibody 9377S from Cell Signaling Technology

Product Specs
ItemPhospho-PKCtheta (Thr538) Antibody
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number9377S
Quantity100 µl
ApplicationsW, W-S
ReactivityH, R, Mk
TargetPKCtheta (Thr538) phosphate
ModificationsPKCtheta (Thr538) phosphate
HostRabbit
NCBI Gene AliasesPRKCT, nPKC-theta
NCBI Full Gene Nameprotein kinase C theta
ClonalityPolyclonal
Research AreaCa, cAMP and Lipid Signaling
Molecular Weight79

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) MAP4K3 inhibits Sirtuin-1 to repress the LKB1–AMPK pathway to promote amino acid-dependent activation of the mTORC1 complexLife Science AllianceAugust 1, 2023Mary Rose Branch, Cynthia L Hsu, Kohta Ohnishi, Wen-Chuan Shen, Elian Lee, Jill Meisenhelder, Brett Winborn, Bryce L Sopher, J Paul Taylor, Tony Hunter, et al.,Cell Signaling Hemagglutinin (HA) (6 × 102),2367,Cell Signaling FLAG (M2),F1804,Sigma-Aldrich Phospho-PKC-θ (T583),9377,Cell Signaling PKC-θ (E117Y),13643,Cell Signaling β-actin,8226,Abcam α-Tubulin,62204,Thermo Fisher Scientific

(2) Black Ginseng Extract Exerts Potentially Anti-Asthmatic Activity by Inhibiting the Protein Kinase Cθ-Mediated IL-4/STAT6 Signaling PathwayInternational Journal of Molecular SciencesJuly 26, 2023Yu Na Song, Jae-Won Lee, Hyung Won Ryu, Jae Kyoung Lee, Eun Sol Oh, Doo-Young Kim, Hyunju Ro, Dahye Yoon, Ji-Yoon Park, Sung-Tae Hong, et al.MA, USA) and C20 (#S6577) from Selleckchem (Houston, TX, USA). Antibodies against phospho(p)-PKCθ (#9377), p-STAT6 (#5654), STAT6 (#5397), p-NF-κB (#3033), and NFAT (#4389) were obtained from Cell Signaling Technology

(3) IL-33 via PKCμ/PRKD1 Mediated α-Catenin Phosphorylation Regulates Endothelial Cell-Barrier Integrity and Ischemia-Induced Vascular LeakageCellsFebruary 23, 2023Deepti Sharma, Geetika Kaur, Shivantika Bisen, Anamika Sharma, Ahmed S. Ibrahim, Nikhlesh K. Singhanti-Phospho-PKCδ (Thr505) (9374), anti-Phospho-PKCδ/θ (Ser643/676) (9376), anti-Phospho-PKCθ (Thr538) (9377), anti-Phospho-PKCζ/λ (Thr410/403) (9378), anti-PKCα (2056), anti-PKCζ (C24E6) (9368), anti-PKD/PKCμ

(4) Mitochondrial reactive oxygen is critical for IL-12/IL-18-induced IFN-γ production by CD4(+) T cells and is regulated by Fas/FasL signalingCell death & diseaseJune 6, 2022Rackov G, Tavakoli Zaniani P, Colomo Del Pino S, Shokri R, Monserrat J, Alvarez-Mon M, Martinez-A C, Balomenos D.(sc-101804) and anti-Caspase 3 (sc-7148) from Santa Cruz Biotechnology; anti-p-AKT (#3787), anti-p-PKC-θ (#9377) and anti-IκBα (#9242) from Cell Signaling; cytochrome C (556433) from BD Biosciences and actin (AC-15)

(5) Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammationeLifeMay 19, 2022Jaime James, Yifei Chen, Clara M Hernandez, Florian Forster, Markus Dagnell, Qing Cheng, Amir A Saei, Hassan Gharibi, Gonzalo Fernandez Lahore, Annika Ã…strand, et al.Healthcare) before imaging on a ChemiDoc XRS+ (Bio-Rad). Antibodies Cell Signaling Technology: p-PKC (9377S), PKC (1364S), Zap70 (2705S), PTPN22 (14693S), p-Src (2101S), LCK (2752S), Fyn (4023S), H2B (12364S).

(6) Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1(G93A) miceBritish journal of pharmacologyApril 1, 2022Scaricamazza S, Salvatori I, Amadio S, Nesci V, Torcinaro A, Giacovazzo G, Primiano A, Gloriani M, Candelise N, Pieroni L, et al.RRID:AB_2798282),WB 1:1000 Primary,pPKCθ (Thr538),Rabbit polyclonal,Cell Signaling Technology (Cat# 9377; RRID:AB_2172071),WB 1:1000 Primary,LRP4,Mouse monoclonal,BioLegend (Cat#832201; RRID:AB_2564954),WB

(7) Tumor-derived NKG2D ligand sMIC reprograms NK cells to an inflammatory phenotype through CBM signalosome activationCommunications biologyJuly 22, 2021Dhar P, Basher F, Ji Z, Huang L, Qin S, Wainwright DA, Robinson J, Hagler S, Zhou J, MacKay S, et al.primary antibodies were purchased from Cell signaling technology (CST): phospho-PKCθ (Thr538) (CST, 9377), PKCθ (CST, 13643), MALT1 (CST, 2494), Bcl10 (CST, 4237), CARD11 (CST, 4435), Fyn (CST, 4023), phospho-NF-κB

(8) Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cellsThe Journal of experimental medicineJuly 5, 2021Sasai M, Ma JS, Okamoto M, Nishino K, Nagaoka H, Takashima E, Pradipta A, Lee Y, Kosako H, Suh PG, et al.were purchased from Santa Cruz Biotechnology. Anti-pZAP70 (#2717), anti-pSLP76 (#14745), anti-PKCθ (#9377), anti-pERK (#4370), anti–p-p38 (#4511), anti-pJNK (#4668), anti–pIκB-α (#9246), anti-NFAT1 (#5861),

(9) Chromatin Priming Renders T Cell Tolerance-Associated Genes Sensitive to Activation below the Signaling Threshold for Immune Response GenesCell reportsJune 9, 2020Bevington SL, Ng STH, Britton GJ, Keane P, Wraith DC, Cockerill PN.were anti-PKCθ clone 27/PKCθ (BD Bioscience), anti-PKCθ pT538 ployclonal (Cell Signaling Technologies #9377) , anti-c-Jun Rabbit monoclonal (Cell Signaling Technologies #9165), anti-c-fos Rabbit monoclonal (Cell Signaling Technologies

(10) Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitorsEMBO molecular medicineJune 8, 2020Fan Z, Tian Y, Chen Z, Liu L, Zhou Q, He J, Coleman J, Dong C, Li N, Huang J, et al.ZAP70 (1:1,000, Cell Signaling Technology, 3165), Phospho‐PKCθ (1:1,000, Cell Signaling Technology, 9377), PKCθ (1:1,000, Cell Signaling Technology, 13643), Phospho‐PLCγ1(1:1,000, Cell Signaling Technology,

(11) PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularizationCell death & diseaseMay 7, 2020Kumar R, Mani AM, Singh NK, Rao GN.obtained from Santa Cruz Biotechnology (Santa Cruz, CA). Anti-JunB (Cat. No. 3753), anti-pPKCθ (Cat. No. 9377), anti-pSTAT3 (Cat. No. 9131), anti-pVEGFR2 (Cat. No. 2478) and anti-VEGFR2 (Cat. No. 2479) antibodies

(12) Targeting PKCθ Promotes Satellite Cell Self-RenewalInternational Journal of Molecular SciencesMarch 31, 2020Anna Benedetti, Piera Filomena Fiore, Luca Madaro, Biliana Lozanoska-Ochser, Marina Bouchéwith anti-PKCθ (#2059, Cell Signaling, Danvers, MA, USA) and anti phospho-PKCθ (Thr538-Cell Signaling #9377) primary antibodies 1:1000 diluted in BSA 5% in TBS 1% tween. HRP-conjugated goat anti–rabbit IgG 1:5000

(13) Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosisNature communicationsJanuary 23, 2020Fu R, Lv WC, Xu Y, Gong MY, Chen XJ, Jiang N, Xu Y, Yao QQ, Di L, Lu T, et al.#9675), acetyl-histone H3 (K14; Abcam, #ab176799), and tri-methyl-histone H3 (K27; Cell Signaling, #9377) at 4 °C under rotation, followed by another incubation with protein A/G beads (Santa Cruz, #sc-2003)

(14) Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα ActivationMolecular therapy oncolyticsDecember 20, 2019Taverner WK, Jacobus EJ, Christianson J, Champion B, Paton AW, Paton JC, Su W, Cawood R, Seymour LW, Lei-Rossmann J.(D4J1N) #90039, phospho-PKCδ (Thr505) #9374, phospho-PKCδ/θ (Ser643/676) #9376, phospho-PKCθ (Thr538) #9377, phospho-PKCζ/λ (Thr410/403) #9378. All PKC antibodies were detected with secondary antibody anti-rabbit

(15) The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in LymphomagenesisImmunityAugust 20, 2019Mintz MA, Felce JH, Chou MY, Mayya V, Xu Y, Shui JW, An J, Li Z, Marson A, Okada T, et al.sc-280; anti-pY493 ZAP70, Cell Signaling Technology, 2704; anti-pT538 PKCθ, Cell Signaling Technology, 9377) in PHEM buffer with 0.02% saponin, 3% BSA for 1 h. Washing was performed 3 times with PHEM buffer,

(16) Compound C Inhibits B16-F1 Tumor Growth in a Syngeneic Mouse Model via the Blockage of Cell Cycle Progression and AngiogenesisCancers (Basel)June 13, 2019Yun Taek Lee, So Hyun Lim, Boram Lee, Insug Kang, Eui-Ju Yeo(#3377), VEGFR2 (#9698), P-Tyr1175-VEGFR2 (#2478), PKC isotypes θ (#2059) and μ (#2052), P-Thr538-PKCθ (#9377), and P-Ser916-PKCμ (#2051) were purchased from Cell Signaling Technology (Danvers, MA, USA). Antibodies

(17) Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages)Aging and diseaseAugust 1, 2018Yang YC, Tsai CY, Chen CL, Kuo CH, Hou CW, Cheng SY, Aneja R, Huang CY, Kuo WW.Phospho-PKC θ, ζ, p62/SQSTM1, LC3B (#2058, #2059, #9368, #9665s, #9664, #9506, #9507, #11967, 3455s, #9377, #2060, #5114, #2775, Cell signaling), PKCα, Phosphor- PKCα (05-154, 06-822, Upstate), Phospho-PKCδ

(18) Lipin-1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagyCancer medicineJune 1, 2018Fan X, Weng Y, Bai Y, Wang Z, Wang S, Zhu J, Zhang F.

(19) An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cellsPLOS ONEJanuary 26, 2018Katharina Schrade et al.

(20) Risk of Myopathy in Patients in Therapy with Statins: Identification of Biological Markers in a Pilot StudyFrontiers in PharmacologyJuly 27, 2017Giulia M. Camerino et al.dilution of primary antibodies were used: rabbit anti-pPKCθ (Thr538) (Cell Signaling Antibodies, c.n. 9377) 1:1000; rabbit anti-PKCθ (Cell Signaling Antibodies c.n. 12206) 1:500; rabbit anti-Clc1 (MyBiosource,

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(1)

9/20/2019Excellent Antibody to Detect Phospho-PKC Theta in Mouse Tissue Raj KumarExcellent antibody. Gives a particular band.
(1)

3/17/2016PKC-theta Antibody Somasundaram RaghavanProtein Kinase C (PKC) are known to activate various cellular responses such as gene expression and proliferation. PKC? is predominently expressed in T lymphocytes and it is known to activate various ... Read Review
(1)

2/11/2016Time-Course Effect of Chemokine on PKC theta Phosphorylation in Human Aortic Smooth Muscle Cells Anonymous Reviewer.We tested the time-course effect of a chemokine on phosphorylation of PKCtheta in Human aortic smooth muscle cells.

Phospho-PKCtheta (Thr538) Antibody

Phospho-PKCtheta (Thr538) Antibody from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-PKCtheta (Thr538) Antibody from Cell Signaling Technology

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