PPARα Polyclonal Antibody 101710 from Cayman Chemical

Product Specs
ItemPPARα Polyclonal Antibody
CompanyCayman Chemical
Price $347.00Supplier Page View Company Product Page
Catalog Number101710
Quantity1 ea
ApplicationsIHC, WB
Format500 µl of Peptide affinity-purified polyclonal antibody
HostRabbit
ImmunogenSynthetic peptide form the N-terminal region of human PPARα
NCBI Full Gene Nameperoxisome proliferator activated receptor alpha
NCBI Gene AliasesNR1C1, PPAR, PPAR-alpha, PPARalpha, hPPAR
ClonalityPolyclonal
Research AreaAdaptive Immunity, Atherosclerosis, Cardiomyopathy, Cardiovascular Diseases, Cardiovascular System, Coronary Artery Disease, Diabetes, Dyslipidemias, Endocrinology & Metabolism, Heart, Hormones & Receptors, Hypertension, Immunology & Inflammation, Innate Immunity, Kidney & Renal Disease, Metabolic Diseases, Myocardial Hypertrophy, Myocardial Infarction, PPARs, RARs, RORs, & RXRs
Molecular Weight~52 kDa
Antibody TypePrimary
Storage-20
OriginUSA
Source/Expression SystemAnimal/Rabbit
ReactivityBaboon, Human, Mouse, Porcine
TargetPPARα

Add to Compare List

Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) PERM1 Gene Delivery via AAV Prevents Heart Failure in a Mouse Model of Pressure OverloadbioRxivOctober 5, 2025Karthi Sreedevi, Ryan Montalvo, Abbigail Doku, Audrey Korte, Rebekah Thomas, Sarah Salama, Steven Burrows, Zhen Yan, Alexey V. Zaitsev, Junco S. Warren#HPA031711, Abcam #ab307302, Abcam #ab191838, Abcam #ab176328, Abcam #ab76228, Cayman product code #101710, Cell Signaling #D9K6P, Cell Signaling #D129C, Abcam #ab110325, Abcam #ab14730, Cell Signaling #E6M5M,

(2) Treatment with crocin attenuates cardiac metabolic disturbances and subsequent inflammation in streptozotocin-induced diabetesMolecular and Cellular BiochemistryJune 3, 2025Dimitra Palioura, Konstantinos Feidantsis, Antigone Lazouincubated overnight with the appropriate primary antibodies: anti-PPARδ (#101720, Cayman), anti-PPARα (#101710, Cayman), anti-phospho Akt (#9271, Cell Signaling), anti-Akt (#4691, Cell Signaling), anti-Glut-4 (#2213,

(3) PCSK9 with a gain of function D374Y mutation aggravates atherosclerosis by inhibiting PPARα expressionSci RepFebruary 26, 2025Yuan Feng Cui, Xiao Cui Chen, Tuoluonayi Mijiti, Abidan Abudurusuli, Li Hui Deng, Xiang Ma, Bangdang Chentissues, as previously described24. Primary antibodies targeting PCSK9 (Novus, NB300-959), PPARα (Cayman, 101710), ApoB (Meridian, K23300R), LDL-R (abcam, ab52818), SR-A (abcam, ab151707), ABCA1 (Novus, NB400-145),

(4) PERM1 regulates mitochondrial energetics through O-GlcNAcylation in the heartJournal of Molecular and Cellular CardiologyJanuary 1, 2025Karthi Sreedevi, Amina James, Sara Do, Shreya Yedla, Sumaita Arowa, Shin-ichi Oka, Adam R. Wende, Alexey V. Zaitsev, Junco S. WarrenThe remaining steps were same as mentioned above for in vivo Co-IP. Anti-PPARα (Cayman; product code #101710) was used as a primary antibody for immunoblotting. To assess the interaction between PERM1 and E2F1,

(5) Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunctionJCI InsightSeptember 5, 2019Charikleia Kalliora et al.generate a chromatin solution that was then used for immunoprecipitation with anti-PPARα antibody (Cayman, 101710), anti-PPARγ (Cell Signaling, 2443), and control IgG (Cell Signaling, 2729). The corrected genomic fragments

(6) Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic CardiomyopathyCell metabolismMay 7, 2019Nakamura M, Liu T, Husain S, Zhai P, Warren JS, Hsu CP, Matsuda T, Phiel CJ, Cox JE, Tian B, et al.,Santa Cruz,sc-5264 Anti-rabbit polyclonal GSK-3β (H-76),Santa Cruz,sc-9166 Anti-rabbit polyclonal PPARα,Cayman Chemical,101710 Anti-rabbit polyclonal PPARα,Abcam,ab24509 Anti-rabbit polyclonal RXRα (D-20),Santa Cruz,sc-553 Anti-rabbit

(7) Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARαNature communicationsApril 11, 2019Liang N, Damdimopoulos A, Goñi S, Huang Z, Vedin LL, Jakobsson T, Giudici M, Ahmed O, Pedrelli M, Barilla S, et al.anti-β-actin (Abcam, ab8226; 1: 30,000), anti-HDAC3 (Santa Cruz, sc11417; 1:3000), anti-PPARα (Cayman, 101710; 1:3000), anti-HA (BioLegend, 901514; 1:5000), and anti-Flag (Sigma-Aldrich, F7425; 1:5000). After several

(8) DEHP deregulates adipokine levels and impairs fatty acid storage in human SGBS-adipocytesScientific reportsFebruary 22, 2018Schaedlich K, Gebauer S, Hunger L, Beier LS, Koch HM, Wabitsch M, Fischer B, Ernst J.Cell Signaling), pSTAT3 (1:1000, mAb#9145, Cell Signaling), SOCS3 (1:250, #2923, Cell signaling), PPARa (1:500, 101710-500, Cayman), PPARg (1:250, mAb2443S, Cell signaling) and PCNA (1:1000, mAB#13110, Cell Signaling).

(9) β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane ReceptorFrontiers in immunologyJanuary 1, 2018Klag T, Thomas M, Ehmann D, Courth L, Mailänder-Sanchez D, Weiss TS, Dayoub R, Abshagen K, Vollmar B, Thasler WE, et al.by Western blot (see Figure S4 in Supplementary Material). Antibodies used: rabbit anti-human PPARα, (CAYMAN No. 101710, dilution 1:500), FXR (Abnova H00009971-M01, dilution 1:1,000), mouse anti-β-Actin (Sigma-Aldrich, A5441,

(10) Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in miceMolecular nutrition & food researchMay 1, 2017Wu L, Guo X, Hartson SD, Davis MA, He H, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, et al.Biotech (Dallas, TX, USA); peroxisome proliferator-activated receptor α (PPARα) antibody (catalog # 101710) was purchased from Cayman (Ann Arbor, MI, USA); Antibodies against β-actin (catalog # 4967), phosphor-Thr172-AMP-activated

(11) REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6Biology openJanuary 15, 2017Chavan R, Preitner N, Okabe T, Strittmatter LM, Xu C, Ripperger JA, Pitteloud N, Albrecht U.anti-HNF6 (G-10) (1:30 dilution; sc-376167, Santa Cruz Biotechnology), with anti-PPARα (1:25 dilution; 101710; Cayman Chemical Company, USA) or with anti-PER2 (1:25 dilution; No. 611138; BD Transduction Laboratories)

(12) Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolismeLifeJuly 1, 2016Rando G, Tan CK, Khaled N, Montagner A, Leuenberger N, Bertrand-Michel J, Paramalingam E, Guillou H, Wahli W.horseradish peroxidase were acquired from Santa Cruz Biotechnology (Dallas, TX). PPARa polyclonal antibody (#101710) was purchased from Cayman Chemical (Ann Arbor, MI). Ex vivo tissue culture Fetal livers (E19.5) were

(13) Antagonizing Peroxisome Proliferator-Activated Receptor α Activity Selectively Enhances Th1 Immunity in Male MiceThe Journal of ImmunologyDecember 1, 2015Monan Angela Zhang, Jeeyoon Jennifer Ahn, Fei Linda Zhao, Thirumahal Selvanantham, Thierry Mallevaey, Nick Stock, Lucia Correa, Ryan Clark, David Spaner, Shannon E Dunn[Cell Signaling]; di/trimethylated histone 3 lysine 27 [H3K27-Me], 9733S, 1:50 [Cell Signaling]; PPARa, 101710, 1:50 [Cayman Chemical]; NCOR1, PAI-844A, 1:50 [Thermo Scientific]; and isotype control IgG from native rabbit

(14) The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genesBMC CancerDecember 1, 2015Maria Thomas, Christine Bayha, Kathrin Klein, Simon Müller, Thomas S. Weiss, Matthias Schwab, Ulrich M. Zangerisoform we used a polyclonal antibody detecting both isoforms (rabbit anti-human PPARa, CAYMAN No. 101710, dilution 1:500). The following additional antibodies and dilutions were used: mouse anti-β-Actin (Sigma-Aldrich,

(15) An Ideal PPAR Response Element Bound to and Activated by PPARαPLOS ONEAugust 4, 2015John Tzeng, Jaemin Byun, Ji Yeon Park, Takanobu Yamamoto, Kevin Schesing, Bin Tian, Junichi Sadoshima, Shin-ichi Okatimes with 1 ml of binding buffer and subjected to Western blot analyses with anti-PPARα (Cayman, #101710) and anti-RXRα (Santa Cruz, ΔN197, sc-774) antibodies. For incubation with WY14,643, 1 μM WY14,643 was

(16) Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunityJournal of Experimental MedicineFebruary 19, 2007Shannon E. Dunn, Shalina S. Ousman, Raymond A. Sobel, Luis Zuniga, Sergio E. Baranzini, Sawsan Youssef, Andrea Crowell, John Loh, Jorge Oksenberg, Lawrence Steinmanconventional methods (Santa Cruz Biotechnology, Inc.) using a rabbit polyclonal PPARα antibody (catalog no. 101710; Cayman Chemical). DNA binding assays. Spleens from five to six mice were pooled, and CD3+ cells were

(17) PERM1 regulates genes involved in fatty acid metabolism in the heart by interacting with PPARα and PGC-1αScientific reportsJanuary 1, 0001"Huang CY, Oka SI, Xu X, Chen CF, Tung CY, Chang YY, Mourad Y, Vehra O, Ivessa A, Yehia G, et al."(Abcam, ab134988), Anti-VLCAD (Abcam, ab155138), Anti-Acadm (Santa Cruz, sc365108), Anti-PPARα (Cayman, 101710 and Novus Biologicals, N300-537), Anti-PGC-1α (Millipore, Ab3242), Anti-GAPDH (Cell Signaling Technology,

Be the First to Write a Review!

PPARα Polyclonal Antibody

PPARα Polyclonal Antibody

PPARα Polyclonal Antibody from Cayman Chemical

Description

Cayman Chemical

Citations (17)

Reviews

PPARα Polyclonal Antibody from Cayman Chemical

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map