Phospho-VEGF Receptor 2 (Tyr1175) (19A10) Rabbit mAb 2478L from Cell Signaling Technology

Product Specs
ItemPhospho-VEGF Receptor 2 (Tyr1175) (19A10) Rabbit mAb
CompanyCell Signaling Technology
Price $947.00 Inquire
Catalog Number2478L
Quantity300 µl
ApplicationsW
ReactivityH, M
TargetVEGFR2 (Tyr1175) phosphate
ModificationsVEGFR2 (Tyr1175) phosphate
HostRabbit
NCBI Gene AliasesCD309, FLK1, VEGFR, VEGFR2
ClonalityMonoclonal
NCBI Full Gene Namekinase insert domain receptor
Research AreaRTK
IsotypeIgG
Clone19A10
Molecular Weight230

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Tumor-like proliferation of CCM3 knockout endothelial cells: insights from semaxinib treatment and transcriptome profiling of co-culturesActa Neuropathol CommunApril 20, 2026Valeriia V. Saenko, Janne L. Feldmann, Dariush Skowronek, Debora Singer, Ole J. Schamuhn, Doreen Biedenweg, Sander Bekeschus, Ute Felbor, Matthias Rath, Robin A. Pilzantibodies against VEGFR2 (#2479S, 1:200, 55B11, Cell Signaling Technology) or p-VEGFR2 (Tyr1175) (#2478S, 1:100, Cell Signaling Technology). After overnight incubation at 4 °C, samples were washed and incubated

(2) Vascular Endothelial Growth Factor-D Improves Lung Vascular Integrity During Acute Lung InjuryCirc ResMarch 13, 2026Yongdae Yoon, Lokesh Sharma, Wenwen Tang, Shannon Kirk, Micha Sam Brickman Raredon, Farida Ahangari, Johad Khoury, Hong Qian, Yunbo Ke, Mohan Tulapurkar, et al.Light Chain 2 (#3674), VEGFR2 (#2479), Tyr951 Phospho-VEGFR2 (#2471), and Tyr1175 Phospho-VEGFR2 (#2478) from Cell Signaling Technology (Danvers); ICAM-1 (Santa Cruz Biotechnologies, # sc-8439); Beta-actin

(3) SHP2 regulates VEGFR2 Y1175/PLCγ signaling to impair tumor endothelial barrier stabilityiScienceFebruary 20, 2026Polina Kremmyda, Sara Owad, Sagnik Pal, Elvira Wildheim, Catarina Chanoca, Cecilia Lindskog, Elin Sjöberganti-VE-Cadherin pY731,In-house,Jin et al.29 Rabbit anti-phospho-VEGFR2 (Tyr1175),Cell Signaling Technology,2478S; RRID: AB_331377 Rabbit anti-VEGFR2,Cell Signaling Technology,2479S; RRID: AB_2212507 Mouse anti-Yes,BD Biosciences

(4) Cytoplasmic LIM domain only 2 enhances tumor endothelial cell migration through integrin β1-mediated focal adhesion signalingActa Neuropathologica CommunicationsFebruary 4, 2026Min Ji Park, Junseok Jang, Cheol Gyu Park, Minseo Gwak, Jong-Whi Park, Hyunggee KimSanta Cruz, USA), anti-ITGB1 (1:2 000) (A19072; ABclonal, South Korea), anti-p-VEGFR2 (Y1175; 1:1 000) (2478S; Cell Signaling, Danvers, MA, USA), anti-VEGFR2 (1:500) (2479S; Cell Signaling Technology, USA), anti-HIF1α

(5) GlycoRNA complexed with heparan sulfate regulates VEGF-A signallingNatureJanuary 28, 2026Peiyuan Chai, Sina Kheiri, Andrew Kuo, Jessica Shah, Lauren Kageler, Ruiqi Ge, Jonathan Perr, Jennifer Porat, Charlotta G. Lebedenko, Joao M. L. Dias, et al.4696S, Cell Signaling Technology; immunoblot 1:500), rabbit monoclonal anti-phospho-VEGFR2(Tyr1175) (2478S, Cell Signaling Technology; immunoblot 1:500), rabbit polyclonal anti-VEGFR2 (26415-AP, Proteintech;

(6) Aberrant VEGFR2 supports tumor growth by extracellular matrix remodelingCell Death & DiseaseJanuary 15, 2026Michela Corsini, Cosetta Ravelli, Mattia Domenichini, Anna Ventura, Camilla Maggi, Elisa Moreschi, Mirko Tamma, Chiara Romani, Claudia Piccoli, Elisabetta Grillo, et al.antibody (pThr202/Thr204, #9101- Cell Signaling Technology, Danvers, MA, USA) antibody or pVEGFR2 (#2478.-Cell Signaling Technology) when indicated. Antigen retrieval was performed in Citrate Buffer solution

(7) Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant GliomaAdvanced ScienceJanuary 1, 2026Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, et al.1:1000); Vinculin (Sigma‐Aldrich, V4505, 1:5000); phospho‐VEGFR2 Tyr 1175 (Cell Signaling Technology, 2478s, 1:1000); total VEGFR2 (Cell Signaling Technology, 2479s, 1:1000), HA‐tag (Cell Signaling Technology,

(8) Farrerol inhibits proliferation and migration of colorectal cancer via the VEGF signaling pathway: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and in vitro experimentsFront PharmacolDecember 3, 2025Longhui Zhang, Qijing Xu, Guanduo Sun, Xiaokang Zhang, Jialong Xue, Chun Yao, Dechun Liu, Jingming ZhaiCo., Ltd. Anti-GAPDH (catalog number. 60004-1-Ig) was purchased from Proteintech Group, Inc. VEGFA (#2478), VEGFR2 (#2479), and p-VEGFR2 (#50661) were purchased from Cell Signaling Technology. 2.11 Cell cuture

(9) Engineering a heparin-mimetic biomaterial to promote tissue vascularizationCommunications BiologyNovember 14, 2025Linqing Li, Jinling Yang, Luba Perry, Jennifer L. Bays, Sangeeta N. Bhatia, Jeroen Eyckmans, Christopher S. Chen(phospho-proteins) and subjected to Western blot analysis using antibodies from Cell Signaling (pVEGFR2, 2478; VEGFR2, 2479; pERK1/2, #4370; ERK1/2, #4695; pAkt, #9271; Akt, #9272; and GAPDH, #5174). The blots

(10) APOA1 binding protein promotes lymphatic cell fate and lymphangiogenesis by relieving caveolae-mediated inhibition of VEGFR3 signalingNat CommunOctober 21, 2025Jun-Dae Kim, Surbhi Chaudhary, Weiqing Chen, Jonathan Astin, Philip S. Crosier, Pengchun Yu, John P. Cooke, Henry J. Pownall, Hugo J. Bellen, Nhat-Tu Le, et al.#ab41927; 1:500), GFP (Invitrogen #MA1-952; 1:1000), VEGFR2 (CST #2479L; 1:1000), pY1175-VEGFR2 (CST #2478S; 1:1000), 4G10 (CST #96215S; 1:1000), GRB2 (CST #3972S; 1:1000), and VEGFR3 (Santa cruz #SC321, 1:400).

(11) Maternal fish oil supplementation enhances nutrient transport in the placenta and milk biosynthesis in the mammary gland via the GPR120 signaling pathwayJournal of advanced researchOctober 1, 2025Li Q, Zhang Q, Su S, Yang S, Shao J, Guan W, Zhang S.Antibody,Cat,Company,Dilution ratio VEGFA,Proteintech,19003-1-AP,1000 VEGFR2,Proteintech,26415-1-AP,1000 p-VEGFR2,CST,2478S,1000 NF-κB,CST,4764S,1000 p-NF-κB,CST,3033S,1000 IκB,Abcam,ab32518,1000 p-IκB,Abcam,ab133462,1000 p38,Proteintech,66234-1-Ig,1000 p-P38,CST,4092S,1000 JNK,CST,9252S,1000 p-JNK,CST,4668S,1000 ERK,CST,9102S,1000 p-ERK,CST,9101S,1000 mTOR,CST,2983S,1000 p-mTOR,CST,5536S,1000 P70

(12) Cancer-associated fibroblast-derived SOD3 enhances lymphangiogenesis to drive metastasis in lung adenocarcinomaAngiogenesisSeptember 30, 2025May Wathone Oo, Takao Hikita, Tomoha Mashima, Kosuke Torigata, Yin Min Thu, Tomohiro Habu, Hotaka Kawai, Toshiaki Ohara, Shuta Tomida, Sachio Ito, et al.SOD3 (1:1000, AF3420, R&D), VEGFA (1:1000, 50661 CST), VEGFR2 (1:1000, 2479, CST), p-VEGFR2 (1:1000, 2478, CST), E-cadherin (1:1000, 13-1900, Thermo Fisher Scientific, MA, USA), N-cadherin (1:1000, 13116, Cell Signaling Technology

(13) Posidonia oceanica Extract Inhibits VEGF-Induced Angiogenic and Oxidative Responses in Human Endothelial Colony-Forming CellsJournal of XenobioticsSeptember 17, 2025Francesca Margheri, Cecilia Anceschi, Elena Frediani, Alessandra Marzoppi, Marzia Vasarri, Donatella Degl’Innocenti, Emanuela Barletta, Anna Laurenzana, Anastasia Chillà4 °C with specific primary antibodies: p-KDR/pVEGFR2 (Rabbit polyclonal 1:1000 Cell Signaling, Cat#2478), KDR/VEGFR2 (Rabbit polyclonal 1:1000 Cell Signaling, Cat#9698), p-AKT and AKT (rabbit, polyclonal

(14) Coinhibition of the MEK/RTK pathway has high therapeutic efficacy in KRAS-mutant non-small cell lung cancerSignal Transduction and Targeted TherapySeptember 12, 2025Jun Lu, Minjuan Hu, Yikai Zhao, Tianqing Chu, Wei Zhang, Yijia Zhou, Xinlei Cai, Jun Wu, Liang Hu, Chunlei Shi, et al.anti-PDGFR (Abcam, ab32570), anti-p-PDGFR (CST, 3170 T), anti-c-Kit (Abcam, ab32363), anti-p-c-Kit (CST, 2478 T), anti-SHP2 (Abcam, ab32083), anti-p-SHP2 (Abcam, ab62322), anti-VEGFR (CST, 2478 T), anti-p-VEGFR

(15) Activin A Prevents Hyperresponsiveness to Vascular Endothelial Growth Factor in Pathologic Blood Vessels by Perturbing the Trafficking of Activated Vascular Endothelial Growth Factor Receptor 2The American Journal of PathologySeptember 1, 2025Basma Baccouche, Maximilian McCann, Janani Rajasekar, Nguyễn Thị Thanh Thị Thanh Nhàn, Kaori Yamada, Andrius Kazlauskaspurchased from SouthernBiotech (Birmingham, AL). Anti-VEGFR2 (247) and anti–phosphorylated VEGFR2 1175 (2478) were purchased from Cell Signaling, Inc. Anti-DEP-1 (sc-21761) was purchased from Santa Cruz Biotechnology

(16) Ginsenoside Rb1 Alleviated the AKI to CKD Transition by Targeting VEGFR2J Cell Mol MedJuly 19, 2025Keying Zhang, Yuwei Ji, Zhangning Fu, Xiaochen Wang, Yifan Zhang, Yan Yang, Ran Liu, Xiangmei Chen, Guangyan Cai, Quan HongVimentin (1:1000, ab92547, Abcam, the UK); eNOS (1:1000, sc376751, Santa Cruz, USA) p‐VEGFR2 (1:1000, 2478s, Cell Signalling Technology, USA); VEGFR2 (1:1000, ab315238, Abcam, the UK); p‐AKT (1:1000, 4060, Cell Signalling

(17) Syndecan-1-mediated loading of VEGF-A into small extracellular vesicles facilitates peritubular capillary repair during AKI-to-CKD transitioniScienceJuly 18, 2025Xin Zhong, Tao-Tao Tang, Yue Zhang, Ding-Ding Xue, An-Ran Shen, Ning Li, Min Wu, Bi-Cheng Liu, Lin-Li LvRRID:AB_2212507 anti-VEGFR2,Santa Cruz Biotechnology,Cat# sc-393163; RRID:AB_2920761 anti-pVEGFR2,Cell Signaling Technology,Cat# 2478; RRID:AB_331377 anti-β-actin,Santa Cruz Biotechnology,Cat# sc-47778; RRID:AB_626632 anti-GAPDH,proteintech,Cat#

(18) Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinomaNat CommunJuly 12, 2025Zhilong Lin, Xiaofei Liu, Houwei Wang, Shumin Li, Ziqiang Miao, Jing Yang, Yuting Zhang, Kai Lei, Yifan Wu, Youmei Kang, et al.ab52615, Abcam, for mice samples), CYP2C8 (16546-1-AP, Proteintech), VEGFR2 (9698S, CST), p-VEGFR2 (2478S, CST), EGFR (ab52894, Abcam), and p-EGFR (ab40815, Abcam). Secondary antibody was then incubated for

(19) Inference of VEGFR2 dimerization kinetics on the cell surface by integrating single-molecule imaging and mathematical modelingbioRxivJune 5, 2025Jaime Guerrero, Zachariah Malik, Fnu Bilal, Soma Jana, Aparajita Dasgupta, Khuloud Jaqamanbuffer was then replaced with 1:100 anti-phospho-VEGFR2 antibody (19A10, Cell Signaling Technology, 2478, Danvers, MA) diluted in blocking buffer to detect phosphorylated VEGFR2. Cells were then washed three

(20) Response of GEM models of neuroblastoma to cabozantinib assessed by multiparametric magnetic resonance imagingNeoplasiaMay 12, 2025Gilberto S. Almeida, Philippa King, Albert Hallsworth, Hannah Webber, Sergey Popov, Susana Miranda, Orli Yogev, Andrew D.J. Pearson, Louis Chesler, Yann Jamin, et al.antibodies (1:1000, Cell Signaling) against MET (#8198), pMET (#3077), VEGFR2 (#9698) and pVEGFR2 (#2478). Following washing, the membrane was incubated with HRP-linked secondary goat antibody for 1 h at room

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Phospho-VEGF Receptor 2 (Tyr1175) (19A10) Rabbit mAb

Phospho-VEGF Receptor 2 (Tyr1175) (19A10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-VEGF Receptor 2 (Tyr1175) (19A10) Rabbit mAb from Cell Signaling Technology

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