HDAC1 Antibody PA1-860 from Thermo Fisher Scientific

Product Specs
ItemHDAC1 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-860
HostRabbit
ClonalityPolyclonal
ApplicationsChIP assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
FormatPBS with 1mg/mL BSA and 0.05% sodium azide
TargetHDAC1
Quantity100 µg
Conjugate/TagUnconjugated
ReactivityCanine, Hamster, Human, Mouse, Rat
Concentration1 mg/mL
ImmunogenSynthetic peptide corresponding to residues C E(467) E K P E A K G V K E E V K L A(482) of human HDAC1
NCBI Full Gene Namehistone deacetylase 1
NCBI Gene AliasesMommeD5, HD1, RPD3L1, KDAC1, GON-10, RPD3, Hdac1-ps
IsotypeIgG
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
PurityAntigen affinity chromatography
Antibody TypePrimary
Storage-20°C, Avoid Freeze/Thaw Cycles

Add to Compare List

Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylationJournal of Molecular Cell BiologyFebruary 13, 2026Jie Fan, Jifei Yang, Zhancheng Tian, Xiaoqiang Zhang, Shuxian Geng, Jianxun Luo, Istvan Boldogh, Qiaoying Zeng, Hong Yin, Guiquan Guan, et al.(PA1-31402, Thermo Fisher Scientific), anti-acetyl-lysine (9441, Cell Signaling Technology), anti-HDAC1 (PA1-860, Invitrogen), anti-HDAC2 (PA1-861, Invitrogen), and anti-HDAC4 (5392S, Cell Signaling Technology). Anti-HDAC5

(2) USP5-dependent HDAC1 promotes cisplatin resistance and the malignant progression of non-small cell lung cancer by regulating RILP acetylation levelsThoracic cancerJanuary 1, 2025Lu R, Jin Y, Zheng M.size of the target protein and incubated with the corresponding primary antibodies targeting HDAC1 (PA1‐860, 1:1000, Thermo Fisher, Waltham, MA, USA), MRP1 (PA5‐30594, 1:1000, Thermo Fisher), USP5 (A301‐543A,

(3) MiRNA-449 family is epigenetically repressed and sensitizes to doxorubicin through ACSL4 downregulation in triple-negative breast cancerCell death discoveryAugust 22, 2024Torres-Ruiz S, Garrido-Cano I, Lameirinhas A, Burgués O, Hernando C, Martínez MT, Rojo F, Bermejo B, Tapia M, Carbonell-Asins JA, et al.TBS-Tween20 and incubated with antibodies against SIRT1 (1:1000, #MA5-15677, Invitrogen), HDAC1 (1:1000, #PA1-860, Invitrogen), acetyl-H3 (1:1000, #ab47915, Abcam, Cambridge, UK), total H3 (1:1000, #9715S, Cell Signaling,

(4) UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168Nature communicationsJune 12, 2024Yalçin Z, Lam SY, Peuscher MH, van der Torre J, Zhu S, Iyengar PV, Salas-Lloret D, de Krijger I, Moatti N, van der Lugt R, et al.

(5) Ketamine Produces Antidepressant Effects by Inhibiting Histone Deacetylases and Upregulating Hippocampal Brain-Derived Neurotrophic Factor Levels in a Diisopropyl Fluorophosphate-Based Rat Model of Gulf War IllnessThe Journal of pharmacology and experimental therapeuticsJanuary 17, 2024Ribeiro-Davis A, Al Saeedy DY, Jahr FM, Hawkins E, McClay JL, Deshpande LS.sections were subsequently subjected to primary antibodies with the following dilutions: HDAC 1 at 1:1500 (PA1-860, ThermoFisher), HDAC 2 at 1:2000 (ab32117, Abcam), HDAC 3 at 1:5000 (ab32369, Abcam), HDAC 4 at 1:1000

(6) A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammationThe Journal of experimental medicineNovember 6, 2023Ralvenius WT, Mungenast AE, Woolf H, Huston MM, Gillingham TZ, Godin SK, Penney J, Cam HP, Gao F, Fernandez CG, et al.

(7) HDAC1-mediated regulation of GABA signaling within the lateral septum facilitates long-lasting social fear extinction in male miceTranslational psychiatryJanuary 17, 2023Bludau A, Neumann ID, Menon R.saline followed by overnight incubation with the following antibodies: rabbit-anti-HDAC1 (Thermo Fisher; PA1-860; 1:2000), HDAC1 phosphorylation on serine residue 421 (rabbit-anti-pHDAC1(S421); Thermo Fisher; PA5-36810;

(8) MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent mannerNature communicationsSeptember 8, 2022Paniagua I, Tayeh Z, Falcone M, Hernández Pérez S, Cerutti A, Jacobs JJL.(5636-I, Millipore, 1:1000), GFP (sc-8334, Santa Cruz, 1:1000), FLAG (F1804, Sigma, 1:1000), HDAC1 (PA1-860, Thermo Fisher Scientific, 1:1000), GAPDH (PA1-987, Thermo Fisher Scientific, 1:10,000). Membranes were

(9) CREB Inactivation by HDAC1/PP1γ Contributes to Dopaminergic Neurodegeneration in Parkinson's DiseaseThe Journal of neuroscience : the official journal of the Society for NeuroscienceJune 1, 2022Xu X, He X, Zhang Z, Chen Y, Li J, Ma S, Huang Q, Li M.

(10) Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell linesNature communicationsMarch 30, 2022Leo IR, Aswad L, Stahl M, Kunold E, Post F, Erkers T, Struyf N, Mermelekas G, Joshi RN, Gracia-Villacampa E, et al.Analysis Software version 4.0.1 (Thermo Fisher Scientific). HDAC1 (Thermo Fisher Scientific, cat. No PA1-860, RRID:AB_2118091, 1:1000 dilution), Phospho-ERK1/2 (Thermo Fisher Scientific, cat. No 14-9109-80, RRID:AB_2572925,

(11) Organic anion transporter 1 is an HDAC4-regulated mediator of nociceptive hypersensitivity in miceNature communicationsFebruary 15, 2022Litke C, Hagenston AM, Kenkel AK, Paldy E, Lu J, Kuner R, Mauceri D.M2), rabbit anti-HA 1:200 (Santa Cruz Cat# sc-805), rabbit anti-HDAC1 1:200 (Thermo Scientific Cat# PA1-860), rabbit anti-HDAC3 1:200 (Cell Signaling Cat# 2632), rabbit anti-HDAC4 1:200 (Cell Signaling Cat# 7628),

(12) PIAS1 Alleviates Hepatic Ischemia-Reperfusion Injury in Mice through a Mechanism Involving NFATc1 SUMOylationDisease markersJanuary 1, 2022Luo J, Li J, Li T, Zhang Z, Chen G, Li Q, Qi H, Si Z.rabbit anti PIAS1 (1: 2000, 23395-1-AP, Proteintech), NFATc1 (1: 1000, #8032S, CST), HDAC1 (1 μg/mL, PA1-860, Thermo Fisher Scientific), IRF-1 (1: 1000, #8478S, CST), tumor necrosis factor alpha (TNF-α, 1: 1000,

(13) Mutation of the murine Prickle1 (R104Q) causes phenotypes analogous to human symptoms of epilepsy and autismExperimental neurologyJanuary 1, 2022Ban Y, Yu T, Wang J, Wang X, Liu C, Baker C, Zou Y.anti-HSP90 beta (ThermoFisher Scientific, PA3–012, lot#TH269376), anti-HDAC1 (ThermoFisher Scientific, PA1–860, lot#UH292524), and anti-GAPDH (Millipore Sigma, MAB374, lot#3291346). 2.5. Overview of mouse behavioral

(14) ATRX proximal protein associations boast roles beyond histone depositionPLoS geneticsNovember 1, 2021Scott WA, Dhanji EZ, Dyakov BJA, Dreseris ES, Asa JS, Grange LJ, Mirceta M, Pearson CE, Stewart GS, Gingras AC, et al.(Santa Cruz, sc-25778, WB: 1:1000), H3.3 (Abcam, ab176840, WB: 1:5000), HDAC1 (Thermo Fisher Scientific, PA1–860, WB: 1:1000), HP1 (Cell Signaling Technology, 2616S, WB: 1:1000), IMP3 (Thermo Fisher Scientific, PA5–26897,

(15) LSD1 Facilitates Pro-Inflammatory Polarization of Macrophages by Repressing CatalaseCellsSeptember 18, 2021Sobczak M, Strachowska M, Gronkowska K, Karwaciak I, Pułaski Ł, Robaszkiewicz A.SuperSignal™ West Pico Chemiluminescent Substrate, TRI Reagent™, PowerUp™ SYBR® Green Master Mix, and anty-HDAC1 (PA1-860) were from Thermofisher Scientific (Thermofisher Scientific, Warsaw, Poland). Advanced TC™ culture plates,

(16) Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transitionBMC cancerMay 29, 2021Ramaker RC, Hardigan AA, Gordon ER, Wright CA, Myers RM, Cooper SJ.were cross-linked, harvested, and DNA was precipitated using a commercial HDAC1 antibody (Invitrogen, PA1860). Libraries were constructed, pooled and sequenced using Illumina NovaSeq single end 75 bp reads. These

(17) Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lungRespiratory researchMarch 17, 2021Lüdtke TH, Wojahn I, Kleppa MJ, Schierstaedt J, Christoffels VM, Künzler P, Kispert A.ThermoFisher Scientific, Waltham, MA, USA), anti-CHD4 (1:200; ab70469, Abcam plc, Cambridge, UK), anti-HDAC1 (1:200; #PA1860, ThermoFisher Scientific), anti-HDAC2 (1:200; #515100, ThermoFisher Scientific), anti-HMGB2 (1:200; #ab124670,

(18) Epstein-Barr virus nuclear antigen 3C (EBNA3C) interacts with the metabolism sensing C-terminal binding protein (CtBP) repressor to upregulate host genesPLoS pathogensMarch 1, 2021Ohashi M, Hayes M, McChesney K, Johannsen E.(Sigma, T6074), and chromatin immunoprecipitation; CtBP1 (EpiGentek, #A2705), HDAC1 (Thermo Fisher PA1-860), and p300 (Bethyl A300-358A) and p53 (Sant Cruz, sc126). CRISPR/Cas9 plasmids and knockout of CDKN2A-ex1α

(19) Chronic Exposure to Alcohol Inhibits New Myelin Generation in Adult Mouse BrainFrontiers in cellular neuroscienceJanuary 1, 2021Guo F, Zhang YF, Liu K, Huang X, Li RX, Wang SY, Wang F, Xiao L, Mei F, Li T.mouse anti-CC1 (1:500, EMD Millipore, Darmstadt, Germany), rabbit anti-HDAC1 (1:200, Invitrogen, Cat: # PA1-860), goat anti-GFAP (1:500, Santa Cruz, Cat: sc-6170), rabbit anti-Iba1 (1:600, Wako, Cat: 019-19741),

(20) HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP-43 proteinopathiesEMBO molecular medicineJune 8, 2020Wu CC, Jin LW, Wang IF, Wei WY, Ho PC, Liu YC, Tsai KJ.following primary antibodies: TDP‐43 (Proteintech, 10782‐2‐AP; Rosemont, IL, 1:300), HDAC1 (Thermo, PA1‐860; Waltham, MA, 1:300), Ki67 (Abcam, ab15580; Cambridge, UK, 1:750), γH2AX (Millipore, 05‐636; Billerica,

Be the First to Write a Review!

WB

ICC/IF

HDAC1 Antibody

HDAC1 Antibody from Thermo Fisher Scientific

Thermo Fisher Scientific

Citations (72)

Reviews

HDAC1 Antibody from Thermo Fisher Scientific

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map